Results 221 to 230 of about 6,603,335 (282)

Global investment in mental health - The Prague Agreement. [PDF]

World Psychiatry
Smith S, Rackham J, Lachman A, Malhotra S, Mazaliauskiene R, Miskimen T, Obindo T, Sanchez-Villanueva T, Seethapathy V, Tomar A, Wasserman D.   +10 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Risk factors for falls and fall-related injuries among community-dwelling older adults in Korea: A longitudinal study. [PDF]

J Korean Gerontol Nurs
Ha B, Kim S.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Patients' Attitudes on the Use of Expanded Outreach to Find a Kidney Donor: A Mixed-Methods Study. [PDF]

Kidney Med
Solbu A, Cadzow RB, Keller M, Mendel R, Breckenridge B, Gardiner H, Kayler LK.   +6 more
europepmc   +1 more source

Clean, Pleasant, Governed: A Critical Discourse Analysis of Bathing Without a Battle. [PDF]

Nurs Inq
Morris P, McCloskey R, Durkee-Lloyd J, O'Regan K.   +3 more
europepmc   +1 more source

Peer support and 2-year abstinence in alcohol use disorder: A nationwide prospective cohort study in recovery-support facilities. [PDF]

PCN Rep
Inoura S, Shimane T, Mizuno S, Matsumoto T.   +3 more
europepmc   +1 more source

The development of the ScoPeO-Kids: A new measure of quality of life for children living in contexts of vulnerability. [PDF]

PLOS Glob Public Health
Higgins J, Poissant L, Legoff S, Archambaud L, Brus A.   +4 more
europepmc   +1 more source