Advanced Experiment Design Strategies for Drug Development
Advanced Intelligent Discovery, EarlyView.Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
Evaluating the impact of mission architecture on crew dynamics in space exploration. [PDF]
NPJ MicrogravityMacRobbie M +4 more
europepmc +1 more source
A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws
Advanced Intelligent Discovery, EarlyView.The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows +7 more
wiley +1 more source
Reality of implementation, barriers, and local-based innovations of stunting reduction programs in Papua region, Indonesia: A systematic review. [PDF]
Narra JMustasmara R, Hariyanti T, Mastuti NL.
europepmc +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
From Village to Clinic: Structural Barriers and Intersecting Challenges in Maternal Healthcare Access in Rural Nepal. [PDF]
Int J Environ Res Public HealthSah LK, Hatzidimitriadou E, Sah P.
europepmc +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao +5 more
wiley +1 more source
From Human Needs to Value-Driven Preferences: Consumers' Willingness to Participate in an Innovative Food Supply Chain Model. [PDF]
FoodsTorquati B +6 more
europepmc +1 more source
A Steerable and Expandable Magnetic Aspiration Catheter for Enhanced Aspiration Thrombectomy
Advanced Intelligent Systems, EarlyView.This article presents a novel magnetic aspiration catheter (MAC) that can be both actively steered and undergo distal‐end expansion via externally applied magnetic fields. The MAC facilitates precise branch selection and enhances clot engagement by improving endovascular navigation and aspiration efficiency. Phantom experiments validate its feasibility
Hakjoon Lee +7 more
wiley +1 more source
Community-based housing alternatives for older adults: towards a conceptual framework for resident involvement. [PDF]
Eur J AgeingStoisser L +3 more
europepmc +1 more source