Results 121 to 130 of about 166,031,618 (286)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Goodness-of-fit test for BTC/BRL.

, 2019
Goodness-of-fit test for BTC/BRL.
Mario I. Contreras-Valdez (6499304), Carlos A. Franco-Ruiz (6499307), José Antonio Núñez (6499301)   +2 more
core   +1 more source

Research on spectrum sensing technologies based on goodness of fit

Dianxin kexue, 2016
Cognitive radio technology has achieved the dynamic allocation of spectrum resources,and improves the utilization rate of spectrum resources.Accurate and efficient spectrum sensing is the key step in cognitive radio.Developing a fast and high-performance
Guangyue LU, Cai XU, Yinghui YE, Yin MI
doaj   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Goodness-of-fit test for BTC/USD.

, 2019
Goodness-of-fit test for BTC/USD.
Mario I. Contreras-Valdez (6499304), Carlos A. Franco-Ruiz (6499307), José Antonio Núñez (6499301)   +2 more
core   +1 more source

Use of Multivariate Adaptive Regression Splines (MARS) and Classification and Regression Tree (CART) Data Mining Algorithms to Predict Live Body Weight of Tswana Sheep

Biology
This study was conducted to (i) determine the association between live body weight (BW) and biometric traits, (ii) examine the effect of biometric traits on BW of Tswana sheep using MARS and CART data mining algorithms, (iii) compare the performance of ...
Monosi Andries Bolowe, Lubabalo Bila, Ketshephaone Thutwa, Patrick Monametsi Kgwatalala   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Goodness-of-fit test for BTC/EUR.

, 2019
Goodness-of-fit test for BTC/EUR.
Mario I. Contreras-Valdez (6499304), Carlos A. Franco-Ruiz (6499307), José Antonio Núñez (6499301)   +2 more
core   +1 more source

Styrking av helseberedskap og krisehåndtering – «mismatch» mellom samarbeidet i EU og EØS?

Internasjonal Politikk
I EU er helsepolitikk, helseberedskap og krisehåndtering primært et nasjonalt anliggende. Over tid har likevel medlemslandene styrket samarbeidet på disse områdene.
Frode Veggeland, Martin Stangborli Time
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source