Results 51 to 60 of about 249,301 (292)
Goodness of fit in models for mortality data [PDF]
, 2008 Mortality data on an aggregate level are characterized by very large sample sizes. For this reason, uninformative outcomes are evident in common Goodness-of-Fit measures.
Durbán, María, Camarda, Carlo Giovanni
core
CoRR, 2022 We develop a new type of generative autoencoder called the Goodness-of-Fit Autoencoder (GoFAE), which incorporates GoF tests at two levels. At the minibatch level, it uses GoF test statistics as regularization objectives. At a more global level, it selects a regularization coefficient based on higher criticism, i.e., a test on the uniformity of the ...
Aaron Palmer +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Random coefficient regressions: parametric goodness of fit tests [PDF]
, 1995 Random coefficient regression models have been applied in different fields during recent years and they are a unifying frame for many statistical models.
Delicado, Pedro, Romo, Juan
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Asymptotic properties of a goodness-of-fit test based on maximum correlations [PDF]
, 2008 We study the efficiency properties of the goodness-of-fit test based on the Qn statistic introduced in Fortiana and Grané (2003) using the concepts of Bahadur asymptotic relative efficiency and Bahadur asymptotic optimality.
Tchirina, Anna V. +2 more
core
, 2006 Increasing attention has been devoted to understanding the process and outcomes of Europeanization, but the measurement of its impact and of the adaptational pressures involved remains elusive. Conventional constructs of Europeanization view 'goodness of
Wishlade, F.G. +4 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source