Results 91 to 100 of about 4,684 (254)

Goodness-of-fit tests for exponential distributions

open access: yes, 2023
The thesis deals with goodness-of-fit tests for the exponential distribution. In the first part, basic concepts are introduced, including their properties.
Hlaváčová, Nikola
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Comparative analysis of Weibull parameter estimation methods for wind resource assessment: A case study in Mexico

open access: yesEnergy Reports
Wind energy, a key renewable source, requires an accurate assessment of its resources, where the Weibull distribution stands out for its ability to model wind variability.
J. Jafet Cruz-Estudillo   +4 more
doaj   +1 more source

Semiparametric Estimates and Goodness-of-Fit Tests for Tire Wear and Failure Time Data

open access: yesNonlinear Analysis, 2002
The goodness-of-fit test for tire wear and failure time data with multiple failure modes is proposed. Parametric estimators of traumatic event cumulative intensities and semiparametric estimates of various reliability characteristics are given and their ...
Rūta Levulienė
doaj   +1 more source

MGOF: Stata module to perform goodness-of-fit tests for multinomial data

open access: yes, 2007
mgof computes goodness-of-fit tests for the distribution of a discrete (categorical, multinomial) variable. The default is to perform classical large sample chi-squared approximation tests based on Pearson's X2 statistic and the log likelihood ratio (G2)
Jann, Ben
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Goodness and Lack of Fit Tests to Pretest Normality when Comparing Means [PDF]

open access: yesOperations Research and Decisions
Previous studies show that processes related to traditional pretests to prove the perfect fulfillment of assumptions in comparison means tests lead to severe alterations in the overall Type I error probability and power.
Pablo Flores, María de Lourdes Palacios
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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