Results 41 to 50 of about 329,541 (261)

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Using large language models to accelerate communication for eye gaze typing users with ALS

Nature Communications
Accelerating text input in augmentative and alternative communication (AAC) is a long-standing area of research with bearings on the quality of life in individuals with profound motor impairments.
Shanqing Cai, Subhashini Venugopalan, Katie Seaver, Xiang Xiao, Katrin Tomanek, Sri Jalasutram, Meredith Ringel Morris, Shaun Kane, Ajit Narayanan, Robert L. MacDonald, Emily Kornman, Daniel Vance, Blair Casey, Steve M. Gleason, Philip Q. Nelson, Michael P. Brenner   +15 more
doaj   +1 more source

Bridging the Privacy Accounting Gap in DP-SGD

The Journal of Privacy and Confidentiality
Differentially Private Stochastic Gradient Descent (DP-SGD) is one of the most widely used algorithms for private machine learning. Due to its efficiency, most practical implementations of DP-SGD shuffle the training examples and divide them into fixed ...
Lynn Chua, Badih Ghazi, Charlie Harrison, Ethan Leeman, Pritish Kamath, Ravi Kumar, Pasin Manurangsi, Amer Sinha, Chiyuan Zhang   +8 more
doaj   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

A mobile-optimized artificial intelligence system for gestational age and fetal malpresentation assessment

Communications Medicine, 2022
Gomes et al. develop machine learning models for gestational age and fetal malpresentation assessment on fetal ultrasound. The authors optimize their system for use in low-resource settings, using novice ultrasound operators, simplified imaging protocols,
Ryan G. Gomes, Bellington Vwalika, Chace Lee, Angelica Willis, Marcin Sieniek, Joan T. Price, Christina Chen, Margaret P. Kasaro, James A. Taylor, Elizabeth M. Stringer, Scott Mayer McKinney, Ntazana Sindano, George E. Dahl, William Goodnight, Justin Gilmer, Benjamin H. Chi, Charles Lau, Terry Spitz, T. Saensuksopa, Kris Liu, Tiya Tiyasirichokchai, Jonny Wong, Rory Pilgrim, Akib Uddin, Greg Corrado, Lily Peng, Katherine Chou, Daniel Tse, Jeffrey S. A. Stringer, Shravya Shetty   +29 more
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Learnable Diffusion Framework for Mouse V1 Neural Decoding

Advanced Science, EarlyView.
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng, Peter S. Schwendeman, Yuanfang Guan   +2 more
wiley   +1 more source

Computational multiqubit tunnelling in programmable quantum annealers

Nature Communications, 2016
Quantum tunnelling may be advantageous for quantum annealing, but multiqubit tunnelling has not yet been observed or characterized theoretically.
Sergio Boixo, Vadim N. Smelyanskiy, Alireza Shabani, Sergei V. Isakov, Mark Dykman, Vasil S. Denchev, Mohammad H. Amin, Anatoly Yu Smirnov, Masoud Mohseni, Hartmut Neven   +9 more
doaj   +1 more source

Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics

Advanced Science, EarlyView.
Deformation‐driven suction cups enable robust, reversible adhesion of wearable electronics to human skin spanning wide mechanical compliance, without adhesives or tight straps. By integrating mechanics modeling, experiments, and contact mechanics theory, this work reveals how cup geometry, substrate compliance, and interfacial adhesion govern suction ...
Seola Lee, Andrew Akerson, Roham Pardakhtim, Ehsan Hajiesmaili, Kevin Rhodes, Zidong Li, Andrew Stanley, Amirhossein Amini, Daniele Piazza, Chiara Daraio, Tianshu Liu   +10 more
wiley   +1 more source