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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Nowcasting with Google Trends : a keyword selection method [PDF]
Search engines, such as Google, keep a log of searches entered into their websites. Google makes this data publicly available with Google Trends in the form of aggregate weekly search term volume.
Ross, Andrew
core
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Nowadays, more and more people surf the Internet seeking health-related information. Information and communication technologies (ICTs) can represent an important opportunities in the field of Public Health and vaccinology. The aim of our current research
Nicola Luigi Bragazzi +8 more
doaj +1 more source
BackgroundThe popularity of dengue can be inferred from Google Trends that summarizes Google searches of related topics. Both the disease and its Google Trends have a similar source of causation in the dengue virus, leading us to hypothesize that dengue ...
Syamsuddin, Muhammad +3 more
doaj +1 more source
Predicting financial markets with Google Trends and not so random keywords
We check the claims that data from Google Trends contain enough data to predict future financial index returns. We first discuss the many subtle (and less subtle) biases that may affect the backtest of a trading strategy, particularly when based on such ...
Ayed, Ahmed Bel Hadj, Challet, Damien
core +3 more sources
Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
Disease names that convey the location of discovery, the discovering scientists, the species of discovery, or the most impacted populations have been increasingly recognized as problematic—often leading to or amplifying xenophobia, disrepute, and stigma.
Erin N. Hulland +4 more
doaj +1 more source
Türkiye’de ve Dünya’da Vergi Af Beklentisinin Popülerlik Analizi
Vergi afları, geçmişten günümüze politikacılar için önemli bir araç olarak varlığını korumaktadır. Bazı ülkelerde, vergi aflarına sıkça başvurulması nedeniyle af kavramı adeta bir kurum haline dönüşmüş ve bu durum mükelleflerin belirli aralıklarla yeni ...
Enes Tekşan, Ercan Yelman
doaj +1 more source
Statistical Laws Governing Fluctuations in Word Use from Word Birth to Word Death [PDF]
How often a given word is used, relative to other words, can convey information about the word’s linguistic utility. Using Google word data for 3 languages over the 209-year period 1800–2008, we found by analyzing word use an anomalous recent change in ...
Petersen, Alexander M. +3 more
core +1 more source

