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Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

'Governing' nanotechnology without government?

Science and Public Policy, 2008
The increasing commercialisation of products containing nanomaterials has been accompanied by growing societal concerns. These concerns have underpinned a debate over the degree to which governments should specifically ‘govern’ or regulate nanotechnology.
Diana M Bowman, Graeme A Hodge
openaire   +2 more sources

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