Results 71 to 80 of about 157,408 (308)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country

Cell Genomics
Summary: The biodiversity crisis is a global phenomenon, and measures to monitor, stop, and revert the impacts on species’ extinction risk are urgently needed.
Sibelle Torres Vilaça, Amanda F. Vidal, Ana Carolina D’Oliveira Pavan, Bruno Marques Silva, Carolina S. Carvalho, Cintia Povill, Danielle Luna-Lucena, Gisele L. Nunes, Henrique Vieira Figueiró, Izabela Santos Mendes, Jose Augusto P. Bittencourt, Lara Gomes Côrtes, Lucas Eduardo Costa Canesin, Renato R.M. Oliveira, Roberta P. Damasceno, Santelmo Vasconcelos, Silvia B. Barreto, Valeria Tavares, Guilherme Oliveira, Amely Branquinho Martins, Alexandre Aleixo   +20 more
doaj   +1 more source

Saving America's Urban Catholic Schools: A Guide for Donors [PDF]

, 2009
Examines the challenges inner-city Catholic schools face and provides guidance on supporting scholarships, performance-driven schools, new models, better governance, teacher recruitment and development, and parental choice policy.
Christopher Levenick, Stephanie Saroki
core  

High-rate, High Temperature Acetotrophic Methanogenesis Governed by a Three Population Consortium in Anaerobic Bioreactors

PLOS ONE, 2016
A combination of acetate oxidation and acetoclastic methanogenesis has been previously identified to enable high-rate methanogenesis at high temperatures (55 to 65°C), but this capability had not been linked to any key organisms. This study combined RNA-stable isotope probing on 13C-labelled acetate and 16S amplicon sequencing to identify the active ...
Ho, Dang, Jensen, Paul, Gutierrez-Zamora, Maria-Luisa, Beckmann, Sabrina, Manefield, Mike, Batstone, Damien   +5 more
openaire   +5 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Decentralisation and devolution in Nicaragua’s North Atlantic autonomous region: Natural resources and indigenous peoples’ rights

International Journal of the Commons, 2012
A number of governments, particularly in Latin America, have begun to recognise the rights of indigenous peoples and traditional communities to the lands on which they live.
Anne M. Larson, Jadder Lewis-Mendoza
doaj   +1 more source

Commercialisation of innovations from the UK National Health Service [PDF]

, 2009
The potential opportunities offered by developing innovative ideas from staff within the UK National Health Service (NHS) was recognised in 2000 and this paper describes a regional organisation, Medipex, which was set up to undertake technology transfer
Clark, Richard, Smith, Michael
core   +1 more source

MULTISTAKEHOLDERS GOVERNANCE FRAMEWORK FOR ONLINE LEARNING MARKETPLACE CONSORTIUM: POWER DYNAMIC PERSPECTIVE

Turkish Online Journal of Distance Education
This paper proposes a governance model framework for online learning marketplaces in Indonesia. This research uses a case study approach to explore a model that is adequate and suitable to be applied in the context of the Indonesia Cyber Education Institute, which was initiated by Universitas Terbuka, Indonesia.
Ira Geraldina, Julia Safitri, Paulina Pannen, Eka Julianti   +3 more
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The impact of blockchain on the banking sector: A systematic review of applications, challenges, and future directions

Asia and the Global Economy
This systematic review evaluates blockchain adoption in the banking and financial sector through 38 peer-reviewed studies published between 2020 and 2024.
Youssef Said, Al mahdi Khaddar, Lahcen Hassine, Ahmed Eddaoui, Tarik Chafiq   +4 more
doaj   +1 more source