Results 51 to 60 of about 45,348 (257)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
SAGE Open, 2013 This article explores the reasons behind the continuation of contentious dam projects in Japanese river basins. Though the River Law of the country was reformed in 1997, and subsequent sociopolitical developments raised hopes that river governance would ...
Abhik Chakraborty
doaj +1 more source
Identifying areas of knowledge governance for successful projects
Journal of Civil Engineering and Management, 2012 Projects undertaken in the project-based industry are characterized by multiple stakeholders, uncertainty, and complexity due to the unique nature of each project. These differences also extend to knowledge movement from one project to another. Increased
Saumyendu Ghosh +2 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The AU, NEPAD and the Promotion of Good Governance in Africa
Nordic Journal of African Studies, 2004 This article argues that good governance has been elusive in much of Africa. The failure of the Organisation for African Unity (OAU) to address Africa’s developmental challenges, including the crisis of governance, led to its demise.
John K. Akokpari
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Investigating the Challenges of Project Governance Processes of IT Projects
Procedia Computer Science, 2018 Abstract This study investigates challenges of project governance processes of Information Technology (IT) projects in organisations. There is still a high prevalent failure rate in implementation of IT projects or initiatives. The failure can be attributed to various factors, which one of the factors could be the existence of Project Governance ...
Refiloe E. Mashiloane, Osden Jokonya
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Implementing social sustainability in area development projects in the Netherlands
PlaNext, 2020 During recent decades, urbanization processes and changing population compositions in European cities have underlined the relevance of social sustainability for urban development.
Celine Janssen, Tom Daamen, Co Verdaas
doaj
DEFINING 'PROJECT GOVERNANCE' FOR LARGE CAPITAL PROJECTS
The South African Journal of Industrial Engineering, 2009 Over the past decade corporate governance has received ample attention. Lately the principles of governance have been applied to other management disciplines, especially project management. The evolution of the concept of 'project governance' resulted in various interpretations and applications of the term, causing confusion among academics and ...
Bekker, M.C. (Michiel Christiaan) +1 more
openaire +3 more sources