Results 51 to 60 of about 45,352 (256)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Appraisal of Governance of Multifarious Infrastructure Projects (MIPs) Delivery in Nigeria
Arid Zone Journal of Engineering, Technology and Environment, 2018 Ineffective governance has been identified as one of the major challenges confronting successful delivery of Multifarious Infrastructure Projects’ (MIPs) and other projects.
G. A. Zarewa
doaj
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Investigating the Challenges of Project Governance Processes of IT Projects
Procedia Computer Science, 2018 Abstract This study investigates challenges of project governance processes of Information Technology (IT) projects in organisations. There is still a high prevalent failure rate in implementation of IT projects or initiatives. The failure can be attributed to various factors, which one of the factors could be the existence of Project Governance ...
Refiloe E. Mashiloane, Osden Jokonya
openaire +1 more source
SAGE Open, 2013 This article explores the reasons behind the continuation of contentious dam projects in Japanese river basins. Though the River Law of the country was reformed in 1997, and subsequent sociopolitical developments raised hopes that river governance would ...
Abhik Chakraborty
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
DEFINING 'PROJECT GOVERNANCE' FOR LARGE CAPITAL PROJECTS
The South African Journal of Industrial Engineering, 2009 Over the past decade corporate governance has received ample attention. Lately the principles of governance have been applied to other management disciplines, especially project management. The evolution of the concept of 'project governance' resulted in various interpretations and applications of the term, causing confusion among academics and ...
Bekker, M.C. (Michiel Christiaan) +1 more
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The relationship between project governance and project success
International Journal of Project Management, 2016 Abstract This study looks at the relationship between project governance and project success from an agency theory and stewardship theory perspective. For that project governance was operationalized respectively as a) the extent of shareholder versus stakeholder orientation and b) the extent of behavior versus outcome control, both exercised by the ...
Joslin, Robert, Müller, Ralf
openaire +2 more sources
The AU, NEPAD and the Promotion of Good Governance in Africa
Nordic Journal of African Studies, 2004 This article argues that good governance has been elusive in much of Africa. The failure of the Organisation for African Unity (OAU) to address Africa’s developmental challenges, including the crisis of governance, led to its demise.
John K. Akokpari
doaj +1 more source