Results 21 to 30 of about 68,330 (260)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
A novel investigation of the influence of corporate governance on firms' credit ratings.
PLoS ONE, 2021 Corporate governance is the way of governing a firm in order to increase its accountability and to avoid any massive damage before it occurs. The aim of this paper is to investigate the impact of capital structure, firms' size, and competitive advantages
Abdullah A K Alkhawaldeh +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Journal of Patient Experience, 2021 Patient Family Advisory Councils (PFACs) are groups of patients, families, and clinical health system leaders collaborating to improve the quality, safety, and experience of care.
Amanda Montalbano MD, MPH, FAAP +6 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Configuration of power in Codeter: an analysis of the Territory of Citizenship Noroeste Colonial-RS
Redes, 2016 This article aims to identify and analyze the configuration of the power in the Governing Board of the Territory Northwest Noroeste Colonial-TC-Norc of Rio Grande do Sul, according to "Power Configuration" proposed by Allebrandt (2010), category from the
Cristiele Tomm Deckert
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
GOVERNANCE STRUCTURE OF NONPROFIT SPORTS ORGANIZATIONS [PDF]
Annals of the University of Craiova: Economic Sciences Series, 2018 Governance structure of nonprofit sports organizations involves three elements: the board, the governing board, and one or more subcommittees. The administrative board is made up of individuals or organizations registered as members, which have the right
Barbu Mihai Constantin Răzvan +1 more
doaj
Corporate Governance and IT Governance: Exploring the Board's Perspective
SSRN Electronic Journal, 2004 Information technology (IT) exceeds half the capital spending of large organizations (US Commerce 2003) and should thus be a major concern of boards. How corporate governance extends into the domain of IT, becoming IT governance, is not widely researched.
Ernest Jordan, David Musson
openaire +3 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source