Results 31 to 40 of about 895,111 (232)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Report. Eighteenth Session of the SPECA Governing Council
, 2023 The Governing Council of the United Nations Special Programme for the Economies of Central Asia (SPECA) will hold its 18th session on 23 November 2023 in Baku, Azerbaijan.
United Nations Special Programme for the Economies of Central Asia (SPECA) +2 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Process philosophy: Organizing mentalities for glimpsing pharmacy practice ‘in flight’
, 2021 There are increasing calls for the development of innovative research methods in pharmacy practice. This commentary seeks to illuminate pathways for ‘thinking differently’ about research approaches for pharmacy practice and social pharmacy by leaning on ...
Woods, P
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Reflections on the Popularity of ‘Conspiracy Mentalities’
, 2020 Moscovici, S. (2006, September). Réflexions sur la popularité des conspiracy mentalities [Reflections on the popularity of conspiracy mentalities] [key lecture presentation].
Gruev-Vintila, Andreea +14 more
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
CEHD Governing Council 2007–2008 Minutes
, 2008 Minutes from CEHD Governing Council meetings, September 19, 2007-April 16, 2008CEHD Governing Council. (2008). CEHD Governing Council 2007–2008 Minutes.
CEHD Governing Council
core