Results 91 to 100 of about 11,016,546 (335)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Who Are the “Middle Class”? [PDF]
, 2007 There is no consensus definition of middle class, neither is there an official government definition. What constitutes the middle class is relative, subjective, and not easily defined.
Cashell, Brian W. +1 more
core +3 more sources
Oral health promotion and homelessness:a theory-based approach to understanding processes of implementation and adoption [PDF]
, 2015 Objective: To use the Theory of Diffusion of Innovations as a framework to explore the qualitative data gleaned from a process evaluation of the Smile4life intervention across Scottish National Health Service (NHS) Boards and to inform future oral health
Coles E +9 more
core +4 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Quasi Government: Hybrid Organizations with Both Government and Private Sector Legal Characteristics [PDF]
, 2008 [Excerpt] This report provides an overview of federally related entities that possess legal characteristics of both the governmental and private sectors.
Kosar, Kevin R
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Journal of Natural Fibers, 2019 The revival of natural dyes in textiles is gaining popularity due to their sustainable nature. The current study has been undertaken to improve the dyeing behaviors of cochineal-based natural dye (carminic acid) for wool dyeing under the influence of ...
Shahid Adeel +7 more
doaj +1 more source
Community Based Cross-Sectional Study to Assess the Health Problems and Quality of Life Among Migrant Construction Workers in Chennai [PDF]
Ķazaķstannyṇ Klinikalyķ MedicinasyBACKGROUND Migrants tend to have an increased risk of physical and mental ill health, but less access to health care services. Hence this study was conducted with the following objectives: to describe the health problems among Migrant construction ...
Veerabathiran Manikandan +7 more
doaj +1 more source