Results 131 to 140 of about 11,016,546 (335)

Continuous vital sign monitoring of acute Lassa fever using wearable biosensor devices in West Africa

Communications Medicine
Background Lassa fever is a fulminant viral illness associated with high in-hospital mortality. This disease constitutes a serious public health concern in West Africa, in particular Nigeria and the Mano River Union region (Guinea, Liberia, and Sierra ...
Brady Page, Raphaëlle Klitting, Matthias G. Pauthner, Steven Steinhubl, Stephan Wegerich, Margaret Kaiser, Foday Alhasan, Edwin Konuwa, Veronica Koroma, Ibrahim Sumah, Jenneh Brima, Tiangay Kallon, Brima Jusu, Sia Mator-Mabay, Mohamed Kamara, Fatima Kamara, Emilia Jaward, Angella Massally, Zainab Kanneh, Michelle McGraw, John Schieffelin, Donald Grant, Kristian G. Andersen   +22 more
doaj   +1 more source

Combination of Interoperability Registries with Process and Data Management Tools for Governmental Services Transformation

, 2009
Yannis Charalabidis, Fenareti Lampathaki, John Psarras   +2 more
openalex   +1 more source

"Japanese At Home In Evacuation City -- A 150-bed hospital has been provided by the U.S. Government for Japanese evacuated from Pacific Coast cities and communities" -- caption on photograph

, 2021
Unknown
openalex   +1 more source

Improving the education of looked after children : a guide for local authorities and service providers [PDF]

, 2009
This guide for practice is based on the key findings of research of Scottish Government-funded pilot projects in 18 Scottish local authorities carried out by the University of Strathclyde between 2006 and 2008.
Connelly, Graham, Furnivall, Judith, The Scottish Government (Funder)   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Government Property and Government Speech [PDF]

, 2011
The relationship between property and speech is close but complicated. Speakers use places and things to deliver their messages, and rely on property rights both to protect expressive acts and to serve as an independent means of expression.
Blocher, Joseph
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

'Nae too bad': job satisfaction and staff morale in Scottish residential child care [PDF]

, 2005
In 2003, the National Children's Bureau and the Social Education Trust published a report - Better Than You Think -on staff morale, qualifications and retention in residential child care in England (Mainey, 2003a; Mainey, 2003b).
Avan, Ghizala, Kendrick, Andrew, Milligan, Ian, Scottish Government (Funder)   +3 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source