Results 131 to 140 of about 4,321,741 (307)
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Northern Territory Government gazette : no. G10
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Northern Territory Government gazette : no. G4
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Northern Territory Government gazette : no. G44
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Northern Territory Government gazette : no. G39
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains many links to external sites.
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ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Úvod do studia neoliberalismu: Inspirace pro antropologii
The aim of this review study is to introduceand examine various concepts of neoliberalism,with special emphasis on the ongoingdiscussions in the field of anthropology.
Ondřej Hejnal
doaj

