Results 61 to 70 of about 8,117,787 (315)

Attorneys’ Opinions Toward Developing a Suicide Preventive Policy and a Review of the Nigerian Suicide Prevention Strategic Framework

Journal of Psychiatry Spectrum
Background: The suicide rate, burden, morbidity, and mortality in Nigeria are alarming. However, until recently, there was no suicide prevention policy in the country.
Oluyemi O. Akanni, Olaitan O. Olusegun, Leroy C. Edozien   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Local Government Authority in Erie and Niagara County Website Report Card [PDF]

, 2018
In February of 2018, the Buffalo Niagara Coalition for Open Government evaluated the websites of fourteen local government Authorities in Erie and Niagara ...
Buffalo Niagara Coalition for Open Government
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Artificial intelligence: opportunities and implications for the future of decision making [PDF]

, 2016
Artificial intelligence has arrived. In the online world it is already a part of everyday life, sitting invisibly behind a wide range of search engines and online commerce sites.
Government, U. K., Science, Office for
core  

A Defense of Student Government [PDF]

, 2018
The Texas ...
Colston, Erica
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Phenomenon of the “dawn attacks operation” as a money politics practices in Indonesian election

Otoritas: Jurnal Ilmu Pemerintahan
The practice of handing out money before voting or dawn raids is still the choice of some legislative candidates to gain votes from citizens. Dawn attacks as a practice of money politics are an act of malpractice that can damage the democratic essence of
Yusa Djuyandi, Diana Mahmuda
doaj   +1 more source