Results 111 to 120 of about 1,641,397 (256)

Exporting Destruction: Export Credits, Illegal Logging and Deforestation [PDF]

open access: yes, 2008
Analyzes case studies of the role of export credit agencies, which make government-subsidized loans to companies doing business in countries considered investment risks, in supporting illegal logging, corruption, and deforestation.

core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

On not becoming an agent of the state: church-related social welfare agency tactics in an era of government contracting [PDF]

open access: yes
Identifies a range of possible tactics that are available to church-related agencies in their engagement with government. Abstract  United States, United Kingdom and Australian literature on the potential, and actual, impacts on not-for profit ...
Doug Hynd
core  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

The role of European HTA agencies in relation to the governance of medical technologies: a discourse analysis of academic literature

open access: yesHealth Economics, Policy and Law
How the role of health technology assessment (HTA) agencies in relation to medical technologies (MedTech) is framed in the literature reflects and influences governance, shaping perceptions and guiding decisions. We identify different academic discourses
Renée Michels   +3 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

The East Midlands: economy a joint response to changing economic circumstances [PDF]

open access: yes, 2008
This document provides an assessment of the regional economy as the UK entered recession in 2008 and sets out how emda, local agencies and Government would work together to tackle the challenges posed by the ...
Department for Business Enterprise and Regulatory Reform   +2 more
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

GOVERNMENT AND NON-GOVERNMENT SUPPORTS FOR SMALL AND MEDIUM ENTERPRISES (SMEs) IN INNOVATION ADOPTION: A CASE OF INDONESIA

open access: yesSpektrum Industri: Jurnal Ilmiah Pengetahuan dan Penerapan Teknik Industri, 2012
This paper attempts to identify supports provided by Government and non-Government agencies in Indonesia. As highlighted in literatures, the characteristics of SMEs are difference to large organizations in particular on their ability to adopt ...
Kifayah Amar
doaj  

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