Results 71 to 80 of about 3,411,720 (258)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Ethics and sustainable government bonds: The retail investors’ perspective
Using the Hunt-Vitell model, this study examines how ethical considerations (ethical sensitivity, perceived utilitarian value as a proxy for ethical egoism, and social investing efficacy reflecting utilitarianism) influence Indonesian retail investors ...
Muhammad Aulia +3 more
doaj +1 more source
The effect of selling government bonds to banks on liquidity [PDF]
In recent years, one of the challenges facing governments has always been the issue of financing the budget deficit. Since 1395, the sale of bonds has started to compensate for the budget deficit and these government bonds have also been sold to banks ...
farhad dejpasand +2 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Money and bonds: an equivalence theorem [PDF]
This paper considers four models in which immortal agents face idiosyncratic shocks and trade only a single risk-free asset over time. The four models specify this single asset to be private bonds, public bonds, public money, or private money ...
Narayana R. Kocherlakota
core
Long Term Government Bonds [PDF]
We study the impact of debt maturity on optimal fiscal policy by focusing on the case where the government issues a bond of maturity N > 1: Isolating these effects helps provide insight into the construction of optimal government debt portfolios. We find
core +2 more sources
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
For the attainment of sustainable development, the e-government phenomenon has become more imperative with its incremental implementations worldwide. In government organizations, e-government services are considered a valuable tool for the delivery of ...
Hasan Zahid, Badariah Haji Din
doaj +1 more source
The capitalization of taxes in bond prices: Evidence from the market for Government of Canada bonds [PDF]
This paper provides estimates of the extent to which corporate and personal income taxes are capitalized in bond prices. The methodology yields estimates of the degree of tax capitalization, rather than an implied tax rate.
Stuart Landon
core
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

