Results 111 to 120 of about 4,849,042 (298)
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Northern Territory Government gazette : no. G24
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Rethinking e-government failure: a readiness-based assessment of Indonesia’s digitalization efforts
This research aims to investigate the factors affecting the success and failure of e-government implementation in four Indonesian regions—South Papua, Papua Highlands, West Java, and Yogyakarta—by analyzing social, economic, and infrastructural ...
Rusmini Rusmini +3 more
doaj +1 more source
Northern Territory Government gazette : no. G41
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Northern Territory Government gazette : no. G42
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Constitutionalism and Transnational Governance Failures
This book explores strategies for limiting transnational market failures, governance failures and constitutional failures impeding protection of the universally agreed sustainable development goals like climate change mitigation and access to justice and transnational rule-of-law.
Ernst-Ulrich Petersmann, Armin Steinbach
openaire +3 more sources
Northern Territory Government gazette : no. G31
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.
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