Results 81 to 90 of about 344,810 (307)

The pre-solicitation phase of Government R and D contracting [PDF]

open access: yes
Decision environment during pre-solicitation phase of procurement cycle in government agency ...
Nichols, G. E., Jr.
core   +1 more source

Pengukuran Kinerja Pengadaan di Pemerintah Kota Semarang Menggunakan Procurement Maturity Model [PDF]

open access: yes, 2016
Procurement Performance Measurement In Semarang City's Government Using Procurement Maturity Model - Semarang City's Government is an agency that is running the procurement activities to improve the welfare and infrastructures in the city of Semarang ...
Arifin, Z. (Zainal)   +2 more
core  

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

Challenges in Designing Public Procurement Linkages: The Case Study of SMEs Preference in China’s Government Procurement [PDF]

open access: yes, 2013
Preferential treatment in government procurement, also known as procurement linkages, is a con-troversial yet popular tool to achieve socio-economic goals, most importantly, affirmative action for certain targeted groups.
Chen, J
core  

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang   +11 more
wiley   +1 more source

Services procurement under the WTO’s agreement on government procurement: whither market access? [PDF]

open access: yes
This paper studies the government procurement of services from foreign suppliers by conducting a statistical analysis of data submitted by Japan and Switzerland to the WTO's Committee on Government Procurement.
Shingal, Anirudh
core   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

open access: yesAdvanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun   +5 more
wiley   +1 more source

Enhancing Usage Behavior of E-Procurement Through Organizational Values

open access: yesJurnal Ilmiah Teknik Industri, 2019
The main purpose of this paper is to examine empirically the influence of organizational factors on the adoption of e-procurement in government institutions.The research design used is a survey research.
Hery Suliantoro   +1 more
doaj   +1 more source

Revisiting Canada's sub central coverage under the WTO Agreement on Government Procurement [PDF]

open access: yes
This article explores the recent changes to Canada’s sub-central government procurement commitments under the World Trade Organization (‘WTO’) Agreement on Government Procurement (‘GPA’).
Collins, D. A.
core  

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

open access: yesAdvanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang   +19 more
wiley   +1 more source

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