A remanufacturing supply chain network with differentiated new and remanufactured products considering consumer preference, production capacity constraint and government regulation. [PDF]
PLoS One, 2023 Zhang X, Zhou G, Cao J, Lu J.
europepmc +1 more source
Molecular Oncology, EarlyView.Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley +1 more source
Government regulations and sickle cell trait [letter] [PDF]
, 1983 Cameron Bf, D. J. Smith, Barbara Cody
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ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Expanding Investment Opportunities Banking System Based on the use of Monetary Instruments Расширение инвестиционных возможностей банковской системы на основе использования инструментов денежно-кредитного регулирования [PDF]
Bìznes Inform, 2012 The paper investigates investment opportunities in the region's banking system and the system of measures of differentiation required reserves, depending on the nature of the transactions carried out by banks.
Zvarich Yelena I.
doaj
SIZE AND HETEROGENEITY MATTER. A MICROSTRUCTURE-BASED ANALYSIS OF REGULATION OF SECONDARY MARKETS FOR GOVERNMENT BONDS. [PDF]
This paper deals with the economics of secondary markets for government bonds. Ultimately, the analysis is shaped by a public policy goal: assessing the elements of a regulatory framework for these markets.
J.Ramon Martinez-Resano
core
Molecular Oncology, EarlyView.Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source
Transcriptional Regulation of Insulin-Like Growth Factor-I Receptor Gene Expression in Prostate Cancer Cells**This work was supported by V.A. Merit Review Program (to S.R.P.), DAMD 17–98-1–8540 (to J.L.W.), NIH DK-52683 (to S.R.P. and J.L.W.), and NIH DK-50810 (to C.T.R.). The content of this report does not necessarily represent the position or the policy of the United States government, and no official endorsement should be inferred. [PDF]
, 2001 Susan E. Damon +6 more
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Is More Government Regulation Needed to Promote E-commerce? [PDF]
E-commerce has experienced tremendous growth over the past few years. Nonetheless, senators, privacy watchdog groups, and the Federal Trade Commission have argued that e-commerce is being held back by consumer worries about online privacy and security ...
Hahn, Robert W., Layne-Farrar, Anne
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