Results 151 to 160 of about 6,625,613 (395)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Introduction to the Political Economy of Environmental Regulations [PDF]

open access: yes
This paper introduces a volume of collected papers on the political economy of environmental regulation: economic analyses of the processes through which political decisions regarding environmental regulation are made, principally in the institutional ...
Stavins, Robert
core  

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Government regulation of private health insurance. [PDF]

open access: yesCochrane Database Syst Rev, 2021
Motaze NV   +4 more
europepmc   +1 more source

Lex Informatica: The Formulation of Information Policy Rules through Technology [PDF]

open access: yes, 1997
Historically, law and government regulation have established default rules for information policy, including constitutional rules on freedom of expression and statutory rights of ownership of information.
Reidenberg, Joel R.
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

ОЦЕНКА УРОВНЯ ГОСУДАРСТВЕННОЙ ПОДДЕРЖКИ ЗЕРНОВОГО ПОДКОМПЛЕКСА АПК КУРСКОЙ ОБЛАСТИ

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2013
Оценка уровня и качества государственной поддержки региона по мнению автора заключается не только в объемах бюджетных ассигнований, но и в не меньшей мере поддержкой рыночных цен на выпускаемую сельхозпроизводителями продукцию.В статье автор применяет ...
Артур Юрьевич Пряничников
doaj  

Boom and Bust of the spanish Economy [PDF]

open access: yes
Spain has experienced many financial crises through its history. These financial crises have varied origins. However, they do have common threads. The current recession and subsequent debt crisis follow the same pattern.
Tomer Shachmurove, Yochanan Shachmurove
core  

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