Results 31 to 40 of about 4,430,131 (277)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Practical Problems of Giving Opinions by Regional Chambers of Accounting on the Possibility of Repayment of Obligations in Local Government Units

open access: yesPrawo Budżetowe Państwa i Samorządu, 2014
Opinions of the regional accounting chambers on the possibility of repayment of the credit, loan or redemption of the securities by local government units have some specific features compared with the other opinions concerning the financial management of
Marcin Tyniewicki
doaj   +1 more source

The Microstructure of Government Securities Markets

open access: yesSocial Science Research Network, 1995
This paper applies the "market microstructure" literature to the specific features of government securities markets and draws implications for the strategy to develop government securities markets.
Peter Dattels
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Conceptual framework for asset back securities rating in Iran Capital Market [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2018
In recent years, the capital market has played a significant role in the financing of the government and the private sector and provided a variety of tools for this purpose, mainly based on the asset backed securities and asset base securities, on the ...
Ghasem Blue   +2 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

The Formation of Tawarruq Security Alternative to Bonds for Fiscal Policy [PDF]

open access: yesمطالعات مالی و بانکداری اسلامی, 2017
With regard to the prohibition of Riba in Islam, it is important to find an alternative to bonds that would be effective for financing the government deficit.
Seyed Mohsen Sajjadi, Mahdi Gholampoor
doaj  

Activities of Ukrainian Banks in the Government Bond Market as a Factor of the Financial Intermediation Paradox [PDF]

open access: yesProblemi Ekonomiki
The relevance of the article’s topic is explained by the matter that Ukrainian banks, despite unfavorable macroeconomic conditions, possess significant liquidity and demonstrate a substantial positive financial outcome.
Verheliuk Yuliia Yu.   +1 more
doaj   +1 more source

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