Results 61 to 70 of about 7,431,624 (306)
Analyzing the Relationship Between Government Size and Unemployment Rate in Iran [PDF]
Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2011 This study investigates the relation between unemployment rate and Government Size in Iran. For that, we have used some VAR models, which include the following variables: government size, measured as total government outlays as a percentage of GDP ...
Ebrahim Ali Razini +2 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Reflections on the Optimal Size of Government [PDF]
, 2000 “It is not always easy to see a common thread in Tullock’s work: he is almost too fertile and throws off so many ideas in all directions that the connecting links between them threaten to disappear from view. Any simple summary of his’ system,’ therefore, must wait on some future effort of his own.
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Economic Performance and Government Size [PDF]
We construct a growth model with an explicit government role, where more government resources reduce the optimal level of private consumption and of output per worker.
António Afonso, João Tovar-Valles
core +2 more sources
The Size and Structure of Government [PDF]
SSRN Electronic Journal, 2010 Does government size and structure adapt to changes in government’s organisational environment (particularly to uncertainty and complexity) as predicted by organisational theory? We find – using a range of statistical analyses – support for each of the major theories of organisation adaptation (the contingency-based view, resource-based view, and ...
Michael, Bryane, Popov, Maja
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Impact of Public Expenditure on Economic Growth: A Review of International Literature
Folia Oeconomica Stetinensia, 2019 Research background: Although a number of studies have been conducted on the relationship between public expenditure and economic growth, it is difficult to tell with certainty whether or not an increase in public expenditure is good for economic growth.
Nyasha Sheilla, Odhiambo Nicholas M.
doaj +1 more source