Results 231 to 240 of about 3,220,898 (292)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Temporal trends and associations between domestic public health spending, donor funding and tuberculosis outcomes in Africa: a serial cross-sectional study (1990-2022). [PDF]

open access: yesBMJ Public Health
Limula C   +8 more
europepmc   +1 more source

The impact of state- versus county-level mask mandates on economic activity during the COVID-19 pandemic. [PDF]

open access: yesPLoS One
Seegert N   +6 more
europepmc   +1 more source

Government Spending and Corporate Innovation

Management Science, 2020
I study the impact of government spending on corporate innovation. Using changes in U.S. Senate committee chairmanships as a source of exogenous variation in state-level federal government expenditures, I find that firms headquartered in states with increases in government spending significantly reduce their innovation output, as measured by their ...
Lei Kong
exaly   +2 more sources

Intratemporal Substitution and Government Spending [PDF]

open access: possibleReview of Economics and Statistics, 1997
In this paper, we examine the idea that a general model of consumption should allow for the direct effect of government expenditures in a two-good permanent-income model. We show, given an assumed preference specification, that there is a cointegration restriction implied by an intraperiod first-order condition of the model. This restriction leads to a
Robert A. Amano, Tony S. Wirjanto
openaire   +1 more source

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