Results 41 to 50 of about 23,970 (277)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Lo internacional y lo global. Gubernamentalidad global: analítica y práctica de gobierno
Colombia Internacional, 2020 Objective/context: This paper is the result of Colombia Internacional’s call to reflect on Global Studies from the South. It is a critical theoretical contribution aiming at putting aside the binary opposing the global and the international.
Mariela Cuadro
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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Neoliberalism, language and governmentality
, 2020 This chapter examines how the concepts of neoliberal governmentality and political rationality contribute to the understanding of neoliberalism as a contemporary form of governance of populations, institutions, practices, language, and subjects, focusing
Del Percio, Alfonso, Martin Rojo, Luisa
core
The governmentality of school autonomy and self-management: A Foucauldian analysis [PDF]
, 2011 Over the past four decades in Australia, many politicians, policy-makers, experts and social commentators have sought to increase the organisational autonomy of public schools and their principals. This trend of shifting the locus of educational decision-
Gobby, Brad
core
Governmentality and political ecology
, 2023 Mobilizing a politico-ecological outlook, the chapter aims at exploring how the category of governmentality – both liberal and neoliberal – can shed light on ecology-related discursive formations that have become mainstream in recent years, namely the ...
Pellizzoni, Luigi, Leonardi, Emanuele
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Metternich 2.0? Surveillance and Panopticism as modes of authoritarian governmentality in Austria
Surveillance & Society, 2017 This paper follows the question if newly introduced surveillance laws and programmes have led to an authoritarian mode of governmentality in Austria in the light of a higher threat perception.
Clemens Binder
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