Results 161 to 170 of about 53,576 (299)

Synthesis of bundle copolymers as an emergent class of copolymer architecture. [PDF]

Nat Commun
Kametani Y, Yamaguchi R, Ando Y, Kawasaki Y, Uemura T.   +4 more
europepmc   +1 more source

Sulfonium‐Based Antimicrobial Block Copolymers: Influence of Hydrophobicity on Biological Activity and Antibiotic Synergy

Macromolecular Rapid Communications, EarlyView.
Sulfonium‐based antimicrobial block copolymers combine an active cationic hydrophobic block with a neutral hydrophilic block to improve cytocompatibility. The hydrophobicity of the sulfonium‐based block controls the activity against S. aureus and E coli.
Sidra Kanwal, Otto Staudhammer, Umer Bin Abdul Aziz, Elisa Quaas, Jörg Rademann, Daniel Klinger   +5 more
wiley   +1 more source

Serum metabolomics identifies GPC depletion in hepatic encephalopathy and its therapeutic potential for cognitive impairment. [PDF]

Front Pharmacol
Chen H, Xing X, Ding X, Xiang G, Li J, Yang Y, Liu Q, Xu K, Lei Q, Li P.   +9 more
europepmc   +1 more source

Polyglycerol‐Based Lipids: A Next‐Generation Alternative to PEG in Lipid Nanoparticles for Advanced Drug Delivery Systems

Macromolecular Rapid Communications, EarlyView.
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger, Rashmi Rashmi, Michael Karimov, Gideon Nölte, Markus Hafke, Ann‐Cathrin Schmitt, David Díaz‐Oviedo, Johannes Köbberling, Rainer Haag   +8 more
wiley   +1 more source

Guías de práctica clínica – GPC para el cáncer gástrico

, 2014
Objetivo: Realizar recomendaciones para la el diagnóstico y tratamiento del cáncer gástrico. Materiales y métodos: El grupo desarrollador de la Guía (GDG) elaboró esta durante el año 2013 de acuerdo a un proceso de adaptación rápida de guías.
Riveros Vega, Javier Humberto, Restrepo Restrepo, Andrés Felipe   +1 more
core  

Development and protective evaluation of mRNA vaccines encoding the glycoprotein precursor of lymphocytic choriomeningitis virus. [PDF]

Virus Res
Lyu Y, Liu J, Qiao Y, Liu M, Yang Y, Li J, Xie Y.   +6 more
europepmc   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

Macromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil‐Bouzas, Andrey Romanyuk, Ivan Torreiro‐Leon, Ana Rey‐Rico, Paco Fernandez‐Trillo   +8 more
wiley   +1 more source

Indirect Roles of Immunophenotypes in the Association Between Glycerophospholipid Metabolism and Endometrial Cancer Risk: A Mendelian Randomization Study. [PDF]

Int J Womens Health
Shen Y, Yan Y, Lin P, Wang Y, Li Y, Li H, Li Y, Dai Y.   +7 more
europepmc   +1 more source

Antimicrobial Cyclic Peptidomimetics

Macromolecular Rapid Communications, EarlyView.
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley   +1 more source

Stabilization of horseradish peroxidase by covalent conjugation with dextran aldehyde against temperature and pH changes

Open Chemistry, 2009
Altikatoglu Melda, Arioz Candan, Basaran Yeliz, Kuzu Huriye   +3 more
doaj   +1 more source