Results 41 to 50 of about 23,099 (204)

Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

Advanced Science, EarlyView.
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng, Evan M. Cale, Amirabbas Maghsoudi, Matthew S. Sutton, Nancy S. Longo, Rebecca A. Gillespie, Lingshu Wang, Ivan Kosik, Sue Chong, Atsuhiro Yasuhara, Tatsiana Bylund, Arne Schön, Prabhanshu Tripathi, Yaroslav Tsybovsky, Haotian Lei, Nicholas C. Morano, Allison B. Lupatkin, Abraham J. Morton, Zabrina C. Lang, Jordan E. Becker, Isabella R. Frascilla, Myungjin Lee, Ning Li, Cuiping Liu, Ryan S. Roark, Chen‐Hsiang Shen, I‐Ting Teng, David J. Van Wazer, Danyi Wang, Lingyuan Wu, Goran Ahlsen, Mike Castro, Haijuan Du, Michael J. Ernandes, Tiansheng Li, Bob C. Lin, Mark K. Louder, Krisha McKee, Jonah S. Merriam, Sijy O'Dell, Li Ou, Sergei Pletnev, David Prikryl, Qi Qiu, Sarah Rubin, Mallika Sastry, Stephen D. Schmidt, Asif Shajahan, Andrea R. Shiakolas, Sanjay Srivatsan, Baoshan Zhang, Qiong Zhou, Mark Connors, Jason G. Gall, Yicheng Guo, Rick K. Huang, Yaoxing Huang, Richard A. Koup, Q. Paula Lei, John R. Mascola, Reda Rawi, Leonid Serebryannyy, Lawrence Shapiro, Zizhang Sheng, David D. Ho, Patrick C. Wilson, Jonathan W. Yewdell, Theodore C. Pierson, Masaru Kanekiyo, Nicole A. Doria‐Rose, Peter D. Kwong, Tongqing Zhou   +71 more
wiley   +1 more source

PbAT: A user‐friendly R/Shiny platform for data‐driven decision support in crop improvement

Applications in Plant Sciences, EarlyView.
Abstract Premise Modern plant breeding requires robust analysis of complex, multi‐environment datasets to identify superior genotypes. Although R offers powerful statistical packages, their use often requires programming expertise. Existing graphical user interface (GUI)‐based tools are either limited in scope or not openly accessible, leaving breeders
Krishnan P. Abhijith, K. K. Vinod, Ranjith Kumar Ellur, K. T. Ravikiran, Rachit Kumar Saxena, Vignesh Muthusamy, S. Gopala Krishnan   +6 more
wiley   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Software Interactions and the GPL

International Free and Open Source Software Law Review, 2010
This article presents the current results of the work carried out within a working group of the European Legal Network of lawyers, facilitated by the Free Software Foundation Europe, whose aim is to provide some general guidance to lawyers and developers working with free software to understand the technical and (potentially) legal effects of the ...
openaire   +2 more sources

Wave Propagation in Rotating Functionally Graded Microbeams Reinforced by Graphene Nanoplatelets

Molecules, 2021
This paper presents a study on wave propagation in rotating functionally graded (FG) microbeams reinforced by graphene nanoplatelets (GPLs). The graphene nanoplatelets (GPLs) are considered to distribute in the diameter direction of the micro-beam in a ...
Tianyu Zhao, Yu Ma, Jiannan Zhou, Yanming Fu   +3 more
doaj   +1 more source

The prevalence of Streptococcus equi subsp. equi carriers in the Netherlands

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies equi (S. equi) carriers are thought to be important drivers for strangles outbreaks. Limited data are available on the prevalence of carriers in European horse husbandry settings. Objectives To estimate the prevalence of S.
R. M. A. C. Houben, E. M. Broens, M. J. Broekhuizen‐Stins, M. M. Sloet van Oldruitenborgh‐Oosterbaan, C. van Maanen, J. A. P. Heesterbeek   +5 more
wiley   +1 more source

Selección de sistemas de gestión de contenidos basados en software libre

Publicaciones en Ciencias y Tecnología, 2007
Se presenta una propuesta de selección basada en el Proceso Analítico Jerárquico (AHP) para comparar Sistemas de Gestión de Contenidos (CMS). Frecuentemente se encuentran métodos de comparación basados en elementos cualitativos, donde se muestra una ...
Edison Sira
doaj  

Reassessing the role of antiphospholipid antibodies in placental‐mediated adverse pregnancy outcomes in systemic lupus erythematosus: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang, Yanling Chang, Ning Zhang, Wen Di, Jiayue Wu   +4 more
wiley   +1 more source

The GPL prevails: An analysis of the first-ever Court decision on the validity and effectivity of the GPL

SCRIPT-ed, 2004
After many years of mostly academic debate about the legal character of the GNU General Public License (GPL) as well as its validity and enforceability, a Munich District Court issued the first-ever judgement dealing with a number of topics in the centre of the discussion.
openaire   +2 more sources

European Circular Economy Structural Typology Based on Multivariate Analysis of Latent Dimensions and Transition Pathways

Sustainable Development, EarlyView.
ABSTRACT Transition towards a circular economy has become a strategic priority for the European Union, although Member States continue to exhibit substantial differences in economic performance, resource efficiency and circular economy implementation. Understanding these structural differences is essential for designing effective policy interventions ...
Nicoleta Barbuta‐Misu, Puiu Lucian Georgescu, Costinela Fortea, Valentin Marian Antohi, Monica Laura Zlati   +4 more
wiley   +1 more source