Results 161 to 170 of about 25,422 (300)

Debris Flows Suppressed Riverine Productivity and Respiration Following High‐Severity Wildfire on the Klamath River, California

open access: yesGeophysical Research Letters, Volume 53, Issue 12, 28 June 2026.
Abstract Wildfires alter terrestrial material and energy inputs to rivers, but impacts to ecosystem metabolism and dissolved oxygen (DO) are not well known due to few river ecosystem response studies during and after wildfires. In summer 2022, wildfire and heavy rains triggered debris flows into the Klamath River, where we compared immediate (days) and
Laurel Genzoli   +3 more
wiley   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

open access: yesAdvanced Science, Volume 13, Issue 34, 19 June 2026.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu   +18 more
wiley   +1 more source

Retrospective Analysis of HER2 Testing, Treatment Patterns, and Clinical Outcomes in Patients With Locally Advanced or Metastatic NSCLC With HER2 Mutations in France

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background HER2 (ERBB2) gene mutations are associated with poor prognosis in non‐small cell lung cancer (NSCLC). It is important to identify patients with HER2‐mutant (HER2m) NSCLC, as new targeted treatment options are emerging. However, HER2 testing in clinical practice varies across regions, and real‐world data on HER2m NSCLC are limited ...
Didier Debieuvre   +9 more
wiley   +1 more source

The Role of Genetic Testing in the Differential Diagnosis of Pustular Dermatoses: A Pediatric Case of Generalized Pustular Psoriasis Associated with the IL36RN Variant. [PDF]

open access: yesJ Clin Med
Markwitz M   +10 more
europepmc   +1 more source

Перспективы введения международного стандарта GPP

open access: yesВестник Казахского Национального медицинского университета, 2013
Resume:In connection with the development of the pharmaceutical industry, introduction of the International standard of GPP(Good Pharmacy Practice ) became a necessity. This standard, along with an increase of the role of the pharmacist, to change the nature of realization of medicinal products and the quality of pharmaceutical services. Implementation
openaire   +1 more source

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