Results 41 to 50 of about 308,238 (274)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

DeLTA: GPU Performance Model for Deep Learning Applications with In-depth Memory System Traffic Analysis

open access: yes, 2019
Training convolutional neural networks (CNNs) requires intense compute throughput and high memory bandwidth. Especially, convolution layers account for the majority of the execution time of CNN training, and GPUs are commonly used to accelerate these ...
Chatterjee, Niladrish   +4 more
core   +1 more source

Medical Ultrasound Imaging: To GPU or Not to GPU?

open access: yesIEEE Micro, 2011
Medical ultrasound imaging stands out from other modalities in providing real-time diagnostic capability at an affordable price while being physically portable. This article explores the suitability of using GPUs as the primary signal and image processors for future medical ultrasound imaging systems.
So, HKH, Yu, ACH, Chen, J, Yiu, BYS
openaire   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Architecture-Aware Optimization on a 1600-core Graphics Processor [PDF]

open access: yes, 2011
The graphics processing unit (GPU) continues to make significant strides as an accelerator in commodity cluster computing for high-performance computing (HPC).
Daga, Mayank   +2 more
core   +1 more source

High Performance Direct Gravitational N-body Simulations on Graphics Processing Units -- II: An implementation in CUDA [PDF]

open access: yes, 2007
We present the results of gravitational direct $N$-body simulations using the Graphics Processing Unit (GPU) on a commercial NVIDIA GeForce 8800GTX designed for gaming computers.
Aarseth   +19 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Interactive Molecular Graphics for Augmented Reality Using HoloLens

open access: yesJournal of Integrative Bioinformatics, 2018
Immersive technologies like stereo rendering, virtual reality, or augmented reality (AR) are often used in the field of molecular visualisation. Modern, comparably lightweight and affordable AR headsets like Microsoft’s HoloLens open up new possibilities
Müller Christoph   +8 more
doaj   +1 more source

Pseudo-random number generators for Monte Carlo simulations on Graphics Processing Units [PDF]

open access: yes, 2010
Basic uniform pseudo-random number generators are implemented on ATI Graphics Processing Units (GPU). The performance results of the realized generators (multiplicative linear congruential (GGL), XOR-shift (XOR128), RANECU, RANMAR, RANLUX and Mersenne ...
Anderson   +25 more
core   +1 more source

GPU Ray Casting

open access: yes, 2009
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Marques, Ricardo   +3 more
openaire   +2 more sources

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