Results 121 to 130 of about 175,847 (284)

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source

CMSA: a heterogeneous CPU/GPU computing system for multiple similar RNA/DNA sequence alignment. [PDF]

BMC Bioinformatics, 2017
Chen X, Wang C, Tang S, Yu C, Zou Q.
europepmc   +1 more source

Superman: Efficient Permanent Computation on Gpus

The permanent is a function, defined for a square matrix, with applications in various domains including quantum computing, statistical physics, complexity theory, combinatorics, and graph theory. Its formula is similar to that of the determinant; however, unlike the determinant, its exact computation is #P-complete, i.e., there is no algorithm to ...
Elbek, Deniz, Taşyaran, Fatih, Uçar, Bora, Kaya, Kamer   +3 more
openaire   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Electromagnetic scattering and imaging simulation of extremely large-scale sea-ship scene based on GPU parallel technology

Journal of Electronic Science and Technology
Aiming to solve the bottleneck problem of electromagnetic scattering simulation in the scenes of extremely large-scale seas and ships, a high-frequency method by using graphics processing unit (GPU) parallel acceleration technique is proposed.
Cheng-Wei Zhang, Zhi-Qin Zhao, Wei Yang, Li-Lai Zhou, Hai-Yu Zhu   +4 more
doaj   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

The Dynamo package for tomography and subtomogram averaging: components for MATLAB, GPU computing and EC2 Amazon Web Services. [PDF]

Acta Crystallogr D Struct Biol, 2017
Castaño-Díez D.
europepmc   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion

Advanced Science, EarlyView.
ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong, Ji Ma, Yidan Lu, Jiahui Zhang, Wanyue Li, Yeke Chen, Teng Zhang, Xuechao Chen, Zhangguo Yu, Peng Lu   +9 more
wiley   +1 more source

Decoding Structure‐Property Relationships in Anion Exchange Membranes via a Chemically Informed Dual‐Channel Graph Attention Network

Advanced Science, EarlyView.
SPARK decodes structure‐property relationships in anion exchange membranes (AEMs) via a chemically informed dual‐channel graph attention network (DEGAT) that explicitly captures microphase separation. It outputs five‐level grades for hydroxide conductivity and alkaline stability and highlights relevant key structural units, enabling robust pre ...
Wanting Chen, Ye Hu, Zijun Xiao, Deming Xia, Bo Pang, Xuemei Wu, Gaohong He   +6 more
wiley   +1 more source