LLM‐Based Scientific Assistants for Knowledge Extraction: Which Design Choices Matter?
A comprehensive framework for optimizing Large Language Models in domain‐specific applications is introduced. The LLM Playground integrates Prompt Engineering, knowledge augmentation, and advanced reasoning strategies to enable systematic comparison of architectures and base models.
David Exler +7 more
wiley +1 more source
A highly energy-efficient multi-core neuromorphic architecture for training deep spiking neural networks. [PDF]
Li M +18 more
europepmc +1 more source
Harnessing Digital Microstructure for Simulation‐Guided Optimization of Permanent Magnets
An experimental‐to‐computational workflow is presented that transforms experimental 3D focused ion beam‐scanning electron microscopy data into a simulation‐ready digital microstructure for multiphase functional materials. Using heavy‐rare‐earth‐free Nd–Fe–B magnets as a model system, the approach quantifies grain connectivity across complex secondary ...
Nikita Kulesh +4 more
wiley +1 more source
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source
Toward cardiac electrophysiology digital twins with an efficient open source scalable solver on GPU clusters. [PDF]
Berg LA +9 more
europepmc +1 more source
This article implements a unified human digital twin framework that integrates cutting edge actuation, sensing, simulation, and bidirectional feedback capability. The approach includes integrating multimodal sensing, AI, and biomechanical simulation into one compact system.
Tajbeed Ahmed Chowdhury +4 more
wiley +1 more source
AmberTorchPB: A Unified Framework for Poisson-Boltzmann-Based Reaction Field Energy Calculation via Tensor Computation. [PDF]
Wu Y, Wang Q, Jiang R, Luo R.
europepmc +1 more source
Holographic Mapping of Orbital Angular Momentum using a Terahertz Diffractive Optical Neural Network
A compact six‐layer diffractive optical neural network enables direct recognition and spatial mapping of terahertz (THz) orbital angular momentum (OAM) beams. Fabricated by 3D printing, the system distinguishes nine OAM modes and their superpositions with high fidelity, good efficiency, and low crosstalk, offering a scalable solution for THz ...
Wei Jia +3 more
wiley +1 more source
Fast segmentation with the NextBrain histological atlas. [PDF]
Puonti O +25 more
europepmc +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source

