Results 231 to 239 of about 8,521 (239)

Tec regulates platelet activation by GPVI in the absence of Btk [PDF]

open access: possibleBlood, 2003
AbstractThe Tec family kinase Btk plays an important role in the regulation of phospholipase Cγ2 (PLCγ2) downstream of the collagen receptor glycoprotein VI (GPVI) in human platelets. Platelets also express a second member of this family, Tec; however, its function has not been analyzed.
Steve P. Watson   +4 more
openaire   +2 more sources

FcRγ-Chain Signals in GPVI-Deficient Platelets.

Blood, 2005
Abstract The receptor glycoprotein VI (GPVI) is required for hemostasis and collagen-induced platelet aggregation. GPVI and FcRγ-chain form a noncovalent signaling complex. Genetic ablation of murine FcRγ-chain prevents expression of GPVI, and immunodepletion of GPVI removes FcRγ chain from platelet membranes.
Carl W. Jackson   +3 more
openaire   +2 more sources

GPVI and collagen: the final word?

Blood, 2022
Alexandre Slater, Martine Jandrot-Perrus
openaire   +2 more sources

DAPT and GPVI: an antiplatelet triple threat

Journal of Thrombosis and Haemostasis, 2023
Andrew, Rickenberg, Michael, Holinstat
openaire   +2 more sources

New role for the GPVI/FcRγ chain complex

Blood, 2006
Comment on Inoue et al, page [1405][1] Previously thought to function only in collagen-induced platelet activation, Inoue and colleagues report that the GPVI/FcRγ chain complex is a crucial component in relaying activation signals following platelet exposure to the extracellular matrix ...
openaire   +2 more sources

GPVI and CLEC-2

2013
Alice Y. Pollitt   +2 more
openaire   +1 more source

GPVI-mediated activation cascade

Reactome - a curated knowledgebase of biological pathways, 2015
openaire   +2 more sources

MURINE GPVI ANTIBODY DOES NOT INDUCE GPVI-DEPLETION BUT REDUCES IN VIVO THROMBOSIS WITH MINIMAL BLEEDING RISK IN RATS

Journal of Thrombosis and Haemostasis, 2007
J. Kambayashi   +8 more
openaire   +2 more sources

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