Results 61 to 70 of about 507,167 (283)

sciapp/gr: v0.58.0

open access: yes, 2021
GR framework: a graphics library for visualisation ...
Josef Heinen   +14 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

sciapp/gr: v0.62.0

open access: yes, 2021
GR framework: a graphics library for visualisation ...
Josef Heinen   +15 more
core   +1 more source

The Use of Passive Samplers to Reveal Industrial and Agricultural Pollution Trends in Swiss Rivers

open access: yesCHIMIA, 2014
This study shows the efficiency of passive sampling to reveal industrial and agricultural pollution trends. Two practical applications for nonpolar and polar contaminants are presented.
Adrien Schopfer   +5 more
doaj   +1 more source

Efficient intent classification and entity recognition for university administrative services employing deep learning models

open access: yesIntelligent Systems with Applications, 2023
The design and implementation of a domain specific conversational agent requires efficient Natural Language Understanding (NLU). The task is harder when multiple languages have to be supported, and training datasets can be beneficial.
S. Rizou   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

sciapp/gr: v0.57.0

open access: yes, 2021
GR framework: a graphics library for visualisation ...
Josef Heinen   +14 more
core   +1 more source

A comparative study of human and zebrafish glucocorticoid receptor activities of natural and pharmaceutical steroids

open access: yesFrontiers in Endocrinology, 2023
IntroductionThe action of environmental steroids on the human glucocorticoid receptor (hGR) has been pointed out with the risk to impair physiological immune and metabolic processes regulated by this nuclear receptor.
Anna Toso   +4 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

sciapp/gr: v0.71.0

open access: yes, 2022
GR framework: a graphics library for visualisation ...
Josef Heinen   +19 more
core   +1 more source

Home - About - Disclaimer - Privacy