Results 61 to 70 of about 507,167 (283)
GR framework: a graphics library for visualisation ...
Josef Heinen +14 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
GR framework: a graphics library for visualisation ...
Josef Heinen +15 more
core +1 more source
The Use of Passive Samplers to Reveal Industrial and Agricultural Pollution Trends in Swiss Rivers
This study shows the efficiency of passive sampling to reveal industrial and agricultural pollution trends. Two practical applications for nonpolar and polar contaminants are presented.
Adrien Schopfer +5 more
doaj +1 more source
The design and implementation of a domain specific conversational agent requires efficient Natural Language Understanding (NLU). The task is harder when multiple languages have to be supported, and training datasets can be beneficial.
S. Rizou +6 more
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
GR framework: a graphics library for visualisation ...
Josef Heinen +14 more
core +1 more source
IntroductionThe action of environmental steroids on the human glucocorticoid receptor (hGR) has been pointed out with the risk to impair physiological immune and metabolic processes regulated by this nuclear receptor.
Anna Toso +4 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
GR framework: a graphics library for visualisation ...
Josef Heinen +19 more
core +1 more source

