Results 101 to 110 of about 848 (243)

Gut microbiome seasonality is associated with dietary plasticity and coexistence in three sympatric Pamir ungulates

iMetaOmics, EarlyView.
This graphical abstract outlines a multi‐omics framework investigating the seasonal dietary composition and gut microbial communities of three coexisting ungulate species inhabiting the extreme high‐altitude Pamir Plateau (Ovis ammon polii, Capra sibirica, and Pseudois nayaur). By integrating dietary DNA metabarcoding, 16S rRNA gene sequencing, shotgun
Dilala Tuoliu, Lijiao Zhang, Muyang Wang, Wenxuan Xu, Kathreen Ruckstuhl, António Alves da Silva, Joana Alves, Hongchen Jiang, Weikang Yang   +8 more
wiley   +1 more source

A Note on Lovász Characterization of Perfect Graphs

Journal of Graph Theory, EarlyView.
ABSTRACT A graph is perfect if, for every induced subgraph, the chromatic number equals the size of its largest clique. In 1972, Lovász established a fundamental characterization of perfect graphs, showing that a graph is perfect if and only if, for every induced subgraph, the product of the size of the largest independent set and the size of the ...
James Alex
wiley   +1 more source

Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao, Edvaldo Vasconcelos Soares Maciel, Frederik Lermyte, Owen S. Skinner   +3 more
wiley   +1 more source

Exteroceptive Reflexes in Stiff Person Syndrome, Other Neurological Conditions and Healthy Controls

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Stiff person syndrome (SPS) is a rare disabling neurological condition with overlapping symptomatology with more common neurological conditions. Exaggerated exteroceptive reflex mechanisms are thought to play a role in its pathophysiology.
Belinda Cruse, Duncan Wilson, Hugo Morales Briceno, Pamela Garcia, Victor Zhang, Jessica Qiu, Tomas Kalincik, Neil Mahant, Victor Shue Chung Fung   +8 more
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

On alpha labeling of tensor product of paths and cycles. [PDF]

Heliyon, 2023
L U, G R.
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Random Generation Topology Coding Technique in Asymmetric Topology Encryption

Mathematics
The security of traditional public key cryptography algorithms depends on the difficulty of the underlying mathematical problems. Asymmetric topological encryption is a graph-dependent encryption algorithm produced to resist attacks by quantum computers ...
Jing Su, Bing Yao
doaj   +1 more source

Inverse Design of Copolyamides via Sequence‐Sensitive Multifidelity Hybrid Models and Teacher–Student Genetic Algorithm

Materials Genome Engineering Advances, EarlyView.
A sequence‐sensitive multi‐fidelity hybrid modeling framework combined with a teacher‐student genetic algorithm enables the inverse design of copolyamides. The hybrid model balances prediction accuracy, sequence‑sensitivity, and computational cost. A two‑tier genetic algorithm can efficiently identify the monomer structures and ratios of copolyamides ...
Sheng Chen, Chaoran Huang, Jianan Hong, Yuquan He, Yuemeng Qiao, Yang Zhao, Siqin Song, Jiaping Lin, Liang Gao   +8 more
wiley   +1 more source

Octagonal prime graceful labeling

Ratio Mathematica
Let G be a graph with p vertices and q edges. Define a bijection f : V (G) → {1, 8, ..., p(3p - 2)} by f(vi) = i(3i - 2) for every i from 1 to p and define a 1 - 1 mapping fopgl ∗ : E(G) → set of natural number N such that f∗(uv) = |f(u) - f(v)| for all ...
V Akshaya
doaj   +1 more source