Results 141 to 150 of about 848 (243)

RelAgent: a multi-agent solution for molecular relationship grounding. [PDF]

open access: yesBioinformatics
Chen R, Wu J, Zhang CJ, Wei XY, Li Q.
europepmc   +1 more source

Pancreatic β‐cell mitogenic regeneration in type 1 diabetes: A preclinical review

open access: yesDiabetic Medicine, EarlyView.
Abstract Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin‐producing pancreatic β‐cells, resulting in hyperglycaemia. The first‐line treatment for symptomatic T1D is exogenous insulin replacement to maintain glycaemic control.
James Cantley   +3 more
wiley   +1 more source

Epigenetic control of cellular plasticity in breast cancer progression

open access: yesThe FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey   +2 more
wiley   +1 more source

The Evolution of Portfolio Theory Under Risk & Uncertainty: From Mean–Variance to AI‐Augmented Investing

open access: yesJournal of Economic Surveys, EarlyView.
ABSTRACT This article summarizes the evolution of portfolio theory from mean–variance optimization to AI‐augmented investment systems. Rather than treating portfolio models as isolated techniques, it organizes the literature as a sequence of responses to different forms of uncertainty: variance, systematic risk, expected‐return estimation error ...
Xuan Feng, Sofia Yang
wiley   +1 more source

The Evolution of Quantitative Equity Investing: Half a Century of Alpha Research and Institutional Adaptation

open access: yesJournal of Economic Surveys, EarlyView.
ABSTRACT This survey interprets the evolution of quantitative equity investing as a history of changing constraints rather than a succession of increasingly complicated forecasting models. Portfolio theory made diversification calculable; characteristic‐based investing converted value, momentum, profitability, and low‐risk effects into scalable ...
Xuan Feng, Julio P. Cardozo, Dehua Xia
wiley   +1 more source

Skolem Graceful Signed Graphs

open access: yesElectronic Notes in Discrete Mathematics, 2003
Mukti Acharya, Tarkeshwar Singh
openaire   +1 more source

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