Results 111 to 120 of about 1,379,256 (326)

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Overcoming Challenges in Small‐Ring Transfer: Direct Decarboxylative Hydroalkylation of Alkenes via Iron‐Thiol Catalysis

Angewandte Chemie, EarlyView.
Herein, we present a catalytic approach for the direct decarboxylation of challenging CF3‐cyclopropyl and cyclobutyl carboxylic acids using cooperative iron‐thiol catalysis. This strategy enables the efficient generation of valuable radicals that can be incorporated into activated and unactivated alkenes, offering access to elusive chemical space ...
Rahul Giri, Po‐Kai Peng, Anthony J. Fernandes, Shijin Yu, Julian G. West, Dmitry Katayev   +5 more
wiley   +2 more sources

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Edge odd graceful labeling of some path and cycle related graphs

AKCE International Journal of Graphs and Combinatorics, 2017
Solairaju and Chithra introduced a new type of labeling of a graph with vertices and edges called an edge odd graceful labeling if there is a bijection from the edges of the graph to the set such that, when each vertex is assigned the sum of all edges ...
S.N. Daoud
doaj   +1 more source

Alpha graphs with different pendent paths

Electronic Journal of Graph Theory and Applications, 2020
Graceful labelings are an effective tool to find cyclic decompositions of complete graphs and complete bipartite graphs. The strongest kind of graceful labeling, the α-labeling, is in the center of the research field of graph labelings, the existence of ...
Christian Barrientos
doaj   +1 more source

Pelabelan Graceful Satu Modulo Pada Beberapa Graf Eule [PDF]

, 2014
. A graph with edges is said to be one modulo graceful graph () if there is a injective function from vertex set of graph to in such a way that induces a function from edge set of graph to defined as is bijective.
Isa, I. (Isa), Ratnasari, L. (Lucia)
core  

Manganese‐Catalyzed Electrochemical Diazidation of Dehydroalanine Peptides

Advanced Science, EarlyView.
A Mn(II)‐catalyzed electrochemical method achieves site‐selective diazidation of dehydroalanine peptides with NaN₃. This radical relay process tolerates diverse functional groups, delivers high yields, and enables precise peptide modification, offering a powerful tool for bioconjugation and therapeutic development.
Xinwei Hu, Chengwei Zheng, Xiaotong Song, Balati Hasimujiang, Mu Chen, Zhixiong Ruan   +5 more
wiley   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

DNA Sequential Logic Circuits for Reversible Counters and Dynamic Biomolecular Sensing

Advanced Science, EarlyView.
In this work, a DNA sequential logic circuit is constructed that combines reusability and autonomy for the first time, including SR (Set‐Reset)‐latches composed of NOR gates, SR‐latches composed of NAND gates, and D (Data)‐latches. After fully utilizing the characteristics of each latch, to counter, toxin and miRNA detection and intracellular dynamic ...
Tianci Xie, Changjiang Li, Minghao Hu, Xingyu Zhong, Junbin Xiao, Zhen Zhang, Ze Wang, Tongbo Wu   +7 more
wiley   +1 more source

Edge Odd Graceful Labeling of Cylinder and Torus Grid Graphs

IEEE Access, 2019
Solairaju and Chithra introduced a new type of labeling of a graph G with p vertices and q edges called an edge odd graceful labeling if there is a bijection f from the edges of the graph to the set {1, 3, ...
S. N. Daoud
doaj   +1 more source