Results 171 to 180 of about 933 (199)

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Toward next-generation hip implants: From failure mechanisms to translational design. [PDF]

J Orthop Translat
Luo Y, Turgeon T, Polyzois I.
europepmc   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Multiscale Analysis of Reinforced Concrete Frames with Embedded Metamaterials Under Progressive Collapse. [PDF]

Materials (Basel)
Long X, Samuneti C, Iyela PM, Kawkabi KW, Ngangura PM, Fan K.   +5 more
europepmc   +1 more source

Multifaceted disruption of AMPA receptor signaling by <i>CACNG8</i> variants: Integrated evidence from human genetics and molecular simulation. [PDF]

Comput Struct Biotechnol J
Alibrandi S, Mordà D, Scimone C, Abate G, Chust IB, Rinaldi C, Poggi L, Scalinci SZ, D'Angelo R, Sidoti A, Donato L.   +10 more
europepmc   +1 more source

CrypToth: Cryptic Pocket Detection through Mixed-Solvent Molecular Dynamics Simulations-Based Topological Data Analysis. [PDF]

J Chem Inf Model
Koseki J, Motono C, Yanagisawa K, Kudo G, Yoshino R, Hirokawa T, Imai K.   +6 more
europepmc   +1 more source

Performance of wall mesh encased stone columns using recycled rubber concrete and asphalt aggregates for sustainable geotechnics. [PDF]

Sci Rep
Hassanzadeh M, Zad A, Ramesht MH, Aslmand M.   +3 more
europepmc   +1 more source

Influence of Rotor-Induced Airflow on Particle Fragmentation in an Impact Crusher: A Computational Fluid Dynamics-Discrete Element Method Study. [PDF]

ACS Omega
Wang X, Huang Y, Zhang F, Meng Q.
europepmc   +1 more source

Multi-omics mendelian randomization integrating GWAS and eQTL data revealed potential drug target for irritable bowel syndrome. [PDF]

Front Genet
Ke H, Chen W, Zhang Q, Liu Z, Wei P, Li L, Yu H, Huang D, Lan C, Xu N, Pi L, Song K.   +11 more
europepmc   +1 more source