Results 61 to 70 of about 350,048 (296)

Factors associated with alteration of nipple or skin sensation and impact of duration of time following nipple-sparing mastectomy (NSM): an analysis of 460 cases with comparison of conventional versus endoscopic- or robotic-assisted NSM

open access: yesWorld Journal of Surgical Oncology, 2023
Background The current study aims to evaluate the nipple and skin sensation following nipple-sparing mastectomy (NSM) and identify patient-, surgical-, or treatment-related factors affecting nipple or skin sensation in this cohort.
Hung-Wen Lai   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

New Ferritic Steel Beyond Grade 92 and its Creep Degradation Assessment by Hardness Method for Grade 91

open access: yes, 2014
The alloy development R&D activities for weld construction components, such as boiler piping and headers of high-efficient fossil-fired power plants have been conducted to introduce creep strength enhanced ferritic (CSEF) steels, grades 91, 92, 122 ...
Tomiko Yamaguchi, Fujimitsu Masuyama
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Quenching and partitioning process of grade 91 stainless steel

open access: yes, 2020
Currently, many researchers and industries are making efforts to construct a new group of Advanced High Strength Steel (AHSS) to overcome disadvantages, such as poor combination of strength and elongation, single phase microstructure and higher cost ...
Shah, Chintan Bimalkumar
core  

Preputial and scrotal cutaneous mast cell tumors in dogs show no evidence of inherently higher biologic malignancy

open access: yesFrontiers in Veterinary Science
Canine genital mast cell tumors (MCTs) have been associated with a poorer prognosis; however, no larger study has focused exclusively on MCTs in this region.
Žiga Žagar   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The Cost of Grade Retention [PDF]

open access: yes
This paper uses administrative longitudinal micro data on the universe of Junior High school students in Uruguay to measure the effect of grade failure on students' subsequent school outcomes.
Marco Manacorda
core  

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