Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Soybean oil fatty acid aromatic amides as dual-functional inhibitors and antimicrobial agents: synthesis, characterization, thermal stability, and performance evaluation. [PDF]
Dadashova NK +10 more
europepmc +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
Umpolung strategy for the electrochemical synthesis of novel anthraquinone-based sulfonamide derivatives: a facile and sustainable strategy. [PDF]
Nematollahi D +2 more
europepmc +1 more source
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley +1 more source
Are Patient-Specific 3-Dimensionally Printed Instrumentations a Viable Solution to Safe Cortical Bone Trajectory Screw Placement? A Systematic Review. [PDF]
Ehioghae M +9 more
europepmc +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Global prevalence and associated risk factors of work-related musculoskeletal disorders among steelworkers: a systematic review and meta-analysis. [PDF]
Lan Y +5 more
europepmc +1 more source
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Implementing a disease management standard operating procedure in a contemporary private pediatric dental practice. [PDF]
Whitlatch K +4 more
europepmc +1 more source

