Results 31 to 40 of about 1,390,742 (240)

Control subgroups and birational extensions of graded rings

International Journal of Mathematics and Mathematical Sciences, 1999
In this paper, we establish the relation between the concept of control subgroups and the class of graded birational algebras. Actually, we prove that if R=⊕σ∈GRσ is a strongly G-graded ring and H⊲G, then the embedding i:R(H)↪R, where R(H)=⊕σ∈HRσ, is a ...
Salah El Din S. Hussein
doaj   +1 more source

Graded Almost Prime Ideals over Non-Commutative Graded Rings

, 2022
The purpose of this article is to define and examine graded almost prime ideals over a non-commutative graded ring, and consider some cases where all graded right ideals of a non-commutative graded ring are graded almost prime.
Shtayat, Jenan, Abu-Dawwas, Rashid, Issa, Ghadeer Bani   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Graded Pseudo Weakly Prime Spectrum Of Graded Topological Modules [PDF]

, 2022
In this study, we introduce graded pseudo weakly prime submodules of G-graded R-modules, which are an extension of graded weakly prime ideals over G-graded rings. On the graded spectrum of graded pseudo weakly prime submodules, we investigate the Zariski
Al-shorman, Tamem, Bataineh, Malik, Bolat, Melis, Ersoy, Bayram Ali   +3 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Prime Ideals and Three-generated Ideals with Large Regularity

Comptes Rendus. Mathématique
Ananyan and Hochster proved the existence of a function $\Phi (m,d)$ such that any graded ideal $I$ generated by $m$ forms of degree at most $d$ in a standard graded polynomial ring satisfies $\mathrm{reg}(I) \le \Phi (m,d)$. Relatedly, Caviglia et.
McCullough, Jason
doaj   +1 more source

DIFFERENT TYPES OF G-PRIME IDEALS ASSOCIATED TO A GRADED MODULE AND GRADED PRIMARY DECOMPOSITION IN A GRADED PRÜFER DOMAIN

International Electronic Journal of Algebra, 2020
Summary: In this paper, we introduce the notion of graded Prüfer domain as a generalization of Prüfer domain to the graded case. We generalize several types of prime ideals associated to a module over a ring to the graded case and prove that most of them coincide over a graded Prüfer domain.
ANSARI, Ajim Uddin, SHARMA, B. K., KUMAR, Shiv Datt   +2 more
openaire   +4 more sources