Results 91 to 100 of about 2,551,566 (242)
Gradient estimate in Orlicz spaces for elliptic obstacle problems with partially BMO nonlinearities
Electronic Journal of Differential Equations, 2018 We prove a global Orlicz estimate for the gradient of weak solutions to a class of nonlinear obstacle problems with partially regular nonlinearities in nonsmooth domains.
Shuang Liang, Shenzhou Zheng
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Estimate of work on Public buildings
Estimate from McGehee, Santa Fe, New Mexico, of work done on the state house, capitol, and penitentiary in Santa Fe. Includes costs, amounts, lumber, arches, windows, doors, lights, basement, excavation, second floor, stone, etc. Architecture.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Gradient Descent-Based Parameter Estimation for Ultra Short Baseline
IEEE AccessThis paper proposes a phase-based pseudorange estimation and a gradient descent-based localization algorithm to improve the positioning performance of the ultra short baseline (USBL) system.
Yongcheol Kim, Haklim Ko, Hojun Lee
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Gradient estimate for Ornstein-Uhlenbeck jump processes
By using absolutely continuous lower bounds of the Lévy measure, explicit gradient estimates are derived for the semigroup of the corresponding Lévy process with a linear drift.
Wang, Feng-Yu
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Discrete versions of the Li-Yau gradient estimate
, 2017 Dier D, Kaßmann M, Zacher R. Discrete versions of the Li-Yau gradient estimate. arXiv:1701.04807. 2017.We study positive solutions to the heat equation on graphs.
Dier, Dominik +2 more
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