Results 71 to 80 of about 1,150,989 (314)
Autofocus method for SAR image with multi-blocks
The Journal of Engineering, 2019 In order to solve synthetic aperture radar image-focus problem when space-variant motion errors could not be ignored, this study proposes a partitioned phase gradient autofocus (PGA) method.
Wei Dong +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
IEEE AccessThis paper presents a methodology and generalized motion framework for quantifying passive biomechanical stability and Range of Motion of human cadaveric specimens, using a position-controlled industrial robot and a wrist-mounted force/torque sensor ...
Aleksander Skrede +4 more
doaj +1 more source
Scholarpedia, 2010 A policy gradient method is a reinforcement learning approach that directly optimizes a parametrized control policy by gradient descent. It belongs to the class of policy search techniques that maximize the expected return of a policy in a fixed policy class while traditional value function approximation approaches derive policies from a value function.
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Solder joint image adaptive block compressive sensing with convex optimisation and Gini index
The Journal of Engineering, 2019 This study aims to improve the performance in solder joint image compression and reconstruction. A novel adaptive block compressive sensing with convex optimisation and Gini index (Ad_BCSGB_Gini) methodology for solder joint image compression and ...
Huihuang Zhao +4 more
doaj +1 more source
Geometry and convergence of natural policy gradient methods. [PDF]
Inf Geom, 2023 Müller J, Montúfar G.
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source