Results 111 to 120 of about 7,285,650 (306)

Management of graft-versus-host disease

Blood Reviews, 2000
The increasing number of allogeneic stem cell transplants, particularly those involving donors other than HLA-identical siblings, has made the management of acute and chronic graft-versus-host disease (GVHD) a continuing problem for transplant experts.
S, Arai, G B, Vogelsang
openaire   +2 more sources

Calcinosis Cutis Related to Sclerodermatous Chronic Graft Versus Host Disease [PDF]

, 2008
We present the case of a 54-year-old woman who had calcinosis cutis related to sclerodermatous chronic graft versus host disease. Graft versus host disease had developed following stem cell transplantation for acute myelogenous leukemia 14 years earlier,
Chew, Felix S., Lipshutz, Gabriel H.
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Intentional donor lymphocyte-induced limited acute graft-versus-host disease is essential for long-term survival of relapsed acute myeloid leukemia after allogeneic stem cell transplantation

Haematologica, 2014
The prognosis of patients with relapsed acute myeloid leukemia after allogeneic transplantation is poor. We hypothesized that initial disease control by effective cytoreduction, followed by rapid induction of a profound allo-immune response by donor ...
Matthias Eefting, Peter A von dem Borne, Liesbeth C de Wreede, Constantijn JM Halkes, Sabina Kersting, Erik WA Marijt, Hendrik Veelken, JH Frederik Falkenburg   +7 more
doaj   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

Enfermedad injerto contra huesped: sus manifestaciones bucales

Revista Cubana de Estomatología
La enfermedad injerto contra huésped es la principal complicación que sufren los pacientes que han recibido trasplante alogénico. Se produce como consecuencia de una reacción inflamatoria exagerada mediada por los linfocitos del donante y estimulada por ...
Claudia Marcela Hernández Cancino, Renata Córdova Petersen, Isabel Nemoto Vergara Sasada, Caroline Siviero Dillenburg, Ingeburg Hellwig   +4 more
doaj  

Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial

Haematologica, 2015
We conducted a phase III study to test the hypothesis that initial therapy with “lower dose” prednisone is effective and safe for patients with newly diagnosed acute graft-versus-host disease.
Marco Mielcarek, Terrence Furlong, Barry E. Storer, Margaret L. Green, George B. McDonald, Paul A. Carpenter, Mary E.D. Flowers, Rainer Storb, Michael Boeckh, Paul J. Martin   +9 more
doaj   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Minimal change nephrotic syndrome after stem cell transplantation: a case report and literature review

Journal of Medical Case Reports, 2007
Graft-versus-host disease is one of the most frequent complications occurring after haematopoietic stem cell transplantation. Recently, renal involvement has been described as a manifestation of chronic graft-versus-host disease.
Silva Sandra, Maximino José, Henrique Rui, Paiva Ana, Baldaia Jorge, Campilho Fernando, Pimentel Pedro, Loureiro Alfredo   +7 more
doaj   +1 more source

Membranous Nephropathy with Crescent after Hematopoietic Cell Transplantation [PDF]

, 2019
A 44-year-old man who received allogenic hematopoietic stem cell transplantation after being diagnosed with acute myeloid leukemia developed nephrosis when the dose of tacrolimus was tapered.
Kitamura, Mineaki, Uramatsu, Tadashi, Nishino, Tomoya, Mukae, Hiroshi, Fukuoka, Junya, Sawayama, Yasushi, Hisano, Satoshi, Miyazaki, Yasushi, Kurobe, Yuka, Obata, Yoko, Abe, Shinichi, Ota, Yuki   +11 more
core   +1 more source