Results 161 to 170 of about 332,330 (302)

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Cell Therapy and Graft Engineering for Chronic Graft-versus-host Disease. [PDF]

Stem Cell Rev Rep
Yang Z, Ming X, Zhou M, Xiao Y.
europepmc   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Myeloid Cell-Targeting PLGA Nanoparticles Ameliorate Acute Graft-Versus-Host Disease. [PDF]

Cancers (Basel)
Galvin JP, Beddow SA, Lust HP, Xu D, Arellano G, Neef T, Lin AY, Miller SD.   +7 more
europepmc   +1 more source

The Esophagus in Graft-Versus-Host Disease

Gastroenterology, 1982
A, Janin-Mercier, A, Devergie, E, Gluckman   +2 more
openaire   +2 more sources

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

BCL2 overexpression in donor lymphocytes reduces the risk of graft-versus-host disease. [PDF]

Blood Adv
Bejarano-García JA, Nufer M, Palacios-Barea MJ, Guijarro-Albaladejo B, Sierro-Martínez B, Bella Á, Robles-Benítez C, García-Guerrero E, Carrasco-Brocal I, Lara-Chica M, Sanoja-Flores L, Mendendez NV, Caballero-Velázquez T, Rodríguez-Gil A, Pérez-Simón JA.   +14 more
europepmc   +1 more source

Dissecting the Influence of Batch Effects on Immunomics Pattern Discovery in High‐Dimensional Mass Cytometry

Cytometry Part A, EarlyView.
ABSTRACT High‐dimensional cytometry, such as mass cytometry (CyTOF), measures protein expression in single cells. When paired with AI‐enhanced data analytics, it facilitates the discovery of immune biomarkers that can assist in diagnosing and treating immune‐related diseases. However, fluctuating instrument readouts, known as batch effects, can obscure
Martin Wasser, Joo Guan Yeo, Valerie Chew, Jing Yao Leong, Salvatore Albani   +4 more
wiley   +1 more source

Assessment of Vedolizumab and UC-MSC interaction and therapeutic potential in acute graft-versus-host-disease. [PDF]

Front Cell Dev Biol
Merlo A, Zilio S, Bernardi M, Catanzaro D, Galla L, Zocca L, Marini O, Piccoli M, Tosetto A, Qi W, Marigo I, Elice F, Astori G.   +12 more
europepmc   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source