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Axatilimab Immunogenicity and Clinical Relevance in Patients with Chronic Graft-Versus-Host Disease. [PDF]
Clin Pharmacol TherYang YO +4 more
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Current Diagnosis and Management of Ocular Graft-Versus-Host Disease at a Tertiary Cancer Center. [PDF]
J Clin MedKhattak EM +6 more
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New England Journal of Medicine, 1991
Graft-versus-host disease, both acute and chronic, continues to be the major complication of human bone marrow transplantation. Improved posttransplant chemoprophylaxis has reduced the incidence of acute graft-versus-host disease, but the incidence of the chronic form of the disease remains unchanged.
J L, Ferrara, H J, Deeg
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Graft-versus-host disease, both acute and chronic, continues to be the major complication of human bone marrow transplantation. Improved posttransplant chemoprophylaxis has reduced the incidence of acute graft-versus-host disease, but the incidence of the chronic form of the disease remains unchanged.
J L, Ferrara, H J, Deeg
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Medicina Clínica (English Edition), 2019
Graft-versus-host disease (GVHD) is the most frequent and potentially fatal complication of an allogeneic hematopoietic progenitor cell transplantation. It appears when immunocompetent T cells from donor origin recognise antigens from recipient origin as foreign. The immune response activates donor T cells and destroys recipient tissues.
David F, Moreno, Joan, Cid
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Graft-versus-host disease (GVHD) is the most frequent and potentially fatal complication of an allogeneic hematopoietic progenitor cell transplantation. It appears when immunocompetent T cells from donor origin recognise antigens from recipient origin as foreign. The immune response activates donor T cells and destroys recipient tissues.
David F, Moreno, Joan, Cid
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Brain, 2010 A major obstacle of allogeneic haematopoietic stem cell transplantation is graft-versus-host disease, an immune-mediated disorder that affects multiple tissues and organs with varying severity. Neurological complications of acute and chronic graft-versus-
Daniel Wolff +2 more
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Current Opinion in Oncology, 1997
Graft-versus-host disease (GVHD) continues to be a major obstacle to the success of allogeneic bone marrow transplantation. Furthermore, several clinical strategies being employed at this time in the field of bone marrow transplantation have had an impact on GVHD.
D C, Marcellus, G B, Vogelsang
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Graft-versus-host disease (GVHD) continues to be a major obstacle to the success of allogeneic bone marrow transplantation. Furthermore, several clinical strategies being employed at this time in the field of bone marrow transplantation have had an impact on GVHD.
D C, Marcellus, G B, Vogelsang
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Current Opinion in Oncology, 1994
Combinations of drugs such as methotrexate, cyclosporin A, and prednisone have reduced the incidence of graft-versus-host disease (GVHD) to 20% to 30%. However, GVDH remains a major complication (up to 90%) following allogeneic bone marrow transplantation from unrelated or mismatched donors.
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Combinations of drugs such as methotrexate, cyclosporin A, and prednisone have reduced the incidence of graft-versus-host disease (GVHD) to 20% to 30%. However, GVDH remains a major complication (up to 90%) following allogeneic bone marrow transplantation from unrelated or mismatched donors.
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Chronic Graft-versus-Host Disease
Current Pharmaceutical Design, 2008Chronic graft-versus-host disease is the most common late, non-relapse complication of transplantation yet it is also one of the least studied. It is the primary cause of morbidity and mortality of long-term survivors of allogeneic bone marrow transplants. Like acute graft-versus-host disease, it does have a strong antitumor effect. The recent National
Javier, Bolaños-Meade +1 more
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Okuläre Graft-versus-Host-Disease
Der Ophthalmologe, 2015Ocular graft versus host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (HSCT) is predominantly an inflammatory and destructive ocular surface disease with increasing incidence. It not only leads to a reduced quality-of-life but can also impair vision and in severe cases lead to blindness. The occurrence of GVHD can lead to
T, Dietrich-Ntoukas, P, Steven
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Journal of the American Academy of Dermatology, 1981
Graft versus host disease (GVHD) occurs in 50% to 70% of patients receiving bone marrow transplants. It can also develop in immunosuppressed patients with malignancies who receive nonirradiated blood transfusions. Most work indicates that the primary mechanism of GVHD is cell-mediated. It is likely that humoral factors are involved as well.
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Graft versus host disease (GVHD) occurs in 50% to 70% of patients receiving bone marrow transplants. It can also develop in immunosuppressed patients with malignancies who receive nonirradiated blood transfusions. Most work indicates that the primary mechanism of GVHD is cell-mediated. It is likely that humoral factors are involved as well.
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