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Pathophysiology of Graft-Versus-Host Disease
Seminars in Hematology, 2006Complications of allogeneic hematopoietic stem cell transplantation (HSCT) remain barriers to its wider application for a variety of diseases. Graft-versus-host disease (GVHD) is the major cause of morbidity and mortality following allogeneic HSCT. GVHD can be considered an exaggerated, undesirable manifestation of a normal inflammatory mechanism, in ...
James L.M. Ferrara, Pavan Reddy
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2013
Allogeneic HSCT representatives are the only curative option for patients with numerous malignant and nonmalignant diseases of the lymphatic and hematopoietic system [1]. Development of a competent immune system from the engraftment of HSCT is mandatory for clinically successful transplant.
John M. Vierling, Ali Raza
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Allogeneic HSCT representatives are the only curative option for patients with numerous malignant and nonmalignant diseases of the lymphatic and hematopoietic system [1]. Development of a competent immune system from the engraftment of HSCT is mandatory for clinically successful transplant.
John M. Vierling, Ali Raza
openaire +2 more sources
2011
THE SKIN is a major target organ for both acute and chronic graft versus host disease (GVHD) after stem cell transplantation (SCT). Although SCT is a life-saving measure and the treatment of choice for many patients with various hematologic malignancies, a high incidence of complications and a transplantation-associated mortality of approximately 30 ...
Ronni Wolf, Jasna Lipozenčić
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THE SKIN is a major target organ for both acute and chronic graft versus host disease (GVHD) after stem cell transplantation (SCT). Although SCT is a life-saving measure and the treatment of choice for many patients with various hematologic malignancies, a high incidence of complications and a transplantation-associated mortality of approximately 30 ...
Ronni Wolf, Jasna Lipozenčić
openaire +2 more sources
1993
The development of nuclear arms at the end of World War II was a major stimulus for research into radiation damage to the hematopoietic system and into the treatment of such damage through bone marrow transplantation [1]. A large body of research with mice, dogs, and monkeys established a “bone marrow syndrome” with death through the complications of ...
L. P. Akard, Q. Chang, J. Jansen
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The development of nuclear arms at the end of World War II was a major stimulus for research into radiation damage to the hematopoietic system and into the treatment of such damage through bone marrow transplantation [1]. A large body of research with mice, dogs, and monkeys established a “bone marrow syndrome” with death through the complications of ...
L. P. Akard, Q. Chang, J. Jansen
openaire +2 more sources
Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021Mitchell H Rosner +2 more
exaly
, 2001