Results 171 to 180 of about 1,940,591 (256)

Graft infection or graft reaction?

, 1979
A perigraft reaction has been described that has been found to be free of infection, with a microscopic picture compatible to an immunologic-like reaction.
Lattimer, G L, Celani, V J, Kaupp, H A, Matulewicz, T J, Kremen, J E   +4 more
core  

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

[18F]Fluorodeoxyglucose Positron Emission Tomography for Diagnosis and Monitoring of Acute Staphylococcus aureus Vascular Graft Infection in a Rat Model. [PDF]

J Infect Dis
Faddy E, Johansen MI, Gadeberg C, Meyer RL, Østergaard L, Bay-Richter C, Jensen LK, Vendelbo MH, Jørgensen NP.   +8 more
europepmc   +1 more source

Clinical outcome of graft removal versus preservation in abdominal aortic graft infection: a systematic review and meta-analysis. [PDF]

Ann Surg Treat Res, 2023
Kim H, Choi HZ, Kwon Y, Labropoulos N.
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Systematic review and meta-analysis of the efficacy and safety of xenopericardium for vascular reconstruction in arterial prosthetic graft infection. [PDF]

Medicine (Baltimore)
Li W, Zhang Z, Ge YY, Tian C.
europepmc   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source

Timely bespoke phage-antibiotic combination to treat refractory Pseudomonas aeruginosa mediastinitis and vascular graft infection. [PDF]

Nat Commun
Chung SJ, Liu Y, Thong S, Zhong Y, Chong ZS, Lim Z, Tan S, Yeo JH, Koh MG, Chua NGS, Ng DHL, Lee WH, Lim TP, Wijaya L, Tan BH, Yap PHE, Aung TT, Ong RT, Ko KKK, Wong THN, Tang YLC, Loh YJ, Tan TE, Tan TT, Kolundzija S, Moreira W, Kwa AL.   +26 more
europepmc   +1 more source

Vascular graft infection with duodenal fistulization 10 years after hybrid endovascular aortic repair with renovisceral debranching: a case report. [PDF]

Gen Thorac Cardiovasc Surg Cases, 2023
Osada H, Yamazaki K, Takeda T, Minatoya K.   +3 more
europepmc   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source