Results 61 to 70 of about 51,422 (314)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Vascular Injuries Caused by Tear Gas Shells: Surgical Challenge and Outcome [PDF]

Iranian Journal of Medical Sciences, 2011
Background: Tear gas shells are used to disperse the mob during any type of street protests. Vascular injuries due to tear gas shells have not been reported.
Mohd Lateef Wani, Ab Gani Ahanga, Gh Nabi Lone, Shyam Singh, Abdul Majeed Dar, Mohd Akbar Bhat, Hakeem Zubair Ashraf, Ifat Irshad   +7 more
doaj  

Angiographic scoring of vascular occlusive disease in the diabetic foot: Relevance to bypass graft patency and limb salvage [PDF]

Journal of Vascular Surgery, 2002
We graded the severity of occlusive disease in foot vessels of patients with diabetes and correlated the scoring obtained with graft patency and limb salvage.In this retrospective review of 199 limbs studied by means of angiography in 117 patients with diabetes mellitus, 124 limbs underwent bypass grafting. Each dorsalis pedis (DP), lateral plantar (LP)
Toursarkissian, Boulos, D'Ayala, Marcus, Stefanidis, Dimitri, Shireman, Paula K., Harrison, Amy, Schoolfield, John, Sykes, Mellick T.   +6 more
openaire   +2 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

New therapeutic options provided by off-label deployment of stent graft for tailored arteriovenous access salvage: Two cases

SAGE Open Medical Case Reports, 2017
A tailored therapy to patient requirements by combining endovascular and surgical steps can be necessary to prolong the life of a vascular access. Stent grafts play a growing role for the therapy of dialytic access complications.
Riccardo Corti, Pietro Quaretti, Franco Galli, Lorenzo Paolo Moramarco, Nicola Cionfoli, Giovanni Leati, Riccardo Corbetta, Matteo Tozzi   +7 more
doaj   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Rattus Model Utilizing Selective Pulmonary Ischemia Induces Bronchiolitis Obliterans Organizing Pneumonia [PDF]

, 2013
Bronchiolitis obliterans organizing pneumonia (BOOP), a morbid condition when associated with lung transplant and chronic lung disease, is believed to be a complication of ischemia.
Clough, Anne V., Cummens, Breana, Densmore, John C., Jacobs, Elizabeth R., Jeziorczak, Paul M., Medhora, Meetha, Pritchard, Kirkwood A., Jr, Rao, Arjun   +7 more
core   +2 more sources

Recent Strategies to Reduce Vein Graft Occlusion: a Need to Limit the Effect of Vascular Damage

European Journal of Vascular and Endovascular Surgery, 2002
Despite early identification and aggressive modification of atherosclerotic risk factors, many patients still require surgical revascularisation for established atherosclerotic vascular disease. However, bypass surgery is hampered by a high incidence of vein graft failure.
Tsui, J.C.S, Dashwood, M.R
openaire   +2 more sources

Vascular replacement using a layered elastin-collagen vascular graft in a porcine model: one week patency versus one month occlusion [PDF]

Organogenesis, 2015
A persistent clinical demand exists for a suitable arterial prosthesis. In this study, a vascular conduit mimicking the native 3-layered artery, and constructed from the extracellular matrix proteins type I collagen and elastin, was evaluated for its performance as a blood vessel equivalent.
Koens, M.J.W., Krasznai, A.G., Hanssen, A.E.J., Hendriks, T., Praster, R., Daamen, W.F., Vliet, J.A. van der, Kuppevelt, T.H. van   +7 more
openaire   +4 more sources

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source